Adapting the HITSystem to Support Prevention of Mother-to-child HIV Transmission

Summary

The purpose of this study is to modify the HITSystem to engage and retain HIV+ pregnant women before, during and after delivery and evaluate the HITSystem impact on prevention of mother-to-child transmission (PMTCT) related behaviors and outcomes. HITSystem 2.0 intervention will support a range of PMTCT outcomes including retention in care, ART adherence, and integration of maternal and pediatric HIV services in low-resource settings.

Conditions

• HIV

Interventions

BEHAVIORAL

HIV Infant Tracking System (HITSystem) 2.0

The HITsystem 2.0 intervention will be designed to: (1) utilize electronic prompts to notify providers and program managers when actions are required, and (2) send text messages to women's mobile phones to (a) motivate adherence to medication, (b) remind women of antenatal (ANC) appointments and medication refills, (c) prompt preparation for a hospital delivery, and (d) support early infant testing. Given advancements in the approach and protocols for care, HITSystem 2.0 will continue to engage mothers and encourage postnatal medication adherence. The researchers will design HITSystem 2.0 to integrate seamlessly into the existing HITSystem to link PMTCT and early infant diagnosis (EID) services through one coordinated system-level intervention.

BEHAVIORAL

Standard of PMTCT care

Pregnant women enrolled in PMTCT services at the control site will receive the current standard of PMTCT care and will not be enrolled in the HITSystem 2.0.

Sponsors & Collaborators

• National Institute of Mental Health (NIMH)

  collaborator NIH

• Kenya Medical Research Institute

  collaborator OTHER

• Global Health Innovations

  collaborator OTHER

• Children's Mercy Hospital Kansas City

  collaborator OTHER

• University of Kansas Medical Center

  lead OTHER

Principal Investigators

• Sarah F Kessler, PhD, MPH · University of Kansas Medical Center

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-08-15

Primary Completion

2019-07-30

Completion

2020-03-20

Countries

• United States
• Kenya

Study Locations