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Impact of Variable Types of Preconditioning Upon the Inotrope Score in Adult Patients, Undergoing Cardiac Surgery

NCT02715869 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2017-12-12

No results posted yet for this study

Summary

Preconditioning (PC) of the heart occurs when brief exposure to a stimulus protects the heart from subsequent ischemia. PC stimulus may be (ischemic ; pharmacologic or Physical).

Conditions

  • Myocardial Ischemia

Interventions

DRUG

A pharmacologic cardiac preconditioning (Sevoflurane)

A Patients are anaesthetized by Sevoflurane more than 1 mac.

PROCEDURE

B ischeamic preconditioning

B ischemic preconditioning will be done after induction and before cardiopulmonary bypass by inflation the cuff of blood pressure above 200mmhg in the lower limb every 5 min for 3cycles

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Emad Zarief Kamel Said, M.D. · Department of Anesthesia, faculty of Medicine, Assiut University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2017-03-31
Completion
2017-06-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02715869 on ClinicalTrials.gov