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Efficacy of Prunus Domestica Extract in BPH

NCT02702947 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2016-11-02

No results posted yet for this study

Summary

Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate Prunus domestica bark contains three groups of active constituents: phytosterols (including beta-sitosterol), pentacyclic triterpenoids (including ursolic and oleaic acids) and ferulic esters of long-chain fatty alcohols (including ferulic esters of docosanol and tetracosanol).

The phytosterols, particularly beta-sitosterol, are found in numerous plants and are anti-inflammatory, inhibiting the synthesis of prostaglandins. Beta-sitosterol has been shown to be useful in cases of BPH by helping to reduce the normally elevated levels of prostaglandins in these patients.

Conditions

  • BPH

Interventions

DIETARY_SUPPLEMENT

Prunus domestica extract

Prosman 1 capsule twice a day

Sponsors & Collaborators

  • Chemical Resources

    lead INDUSTRY

Principal Investigators

  • Dr. Satyanarayan sankhwar, M.S., M.Ch. · King George's Medical University, Lucknow, UP, India

  • Dr. Narsingh Verma, M.D. · King George's Medical University, Lucknow, UP, India

Study Design

Allocation
NA
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
40 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2016-05-31
Completion
2016-09-30

Countries

  • India

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02702947 on ClinicalTrials.gov