Applicability of the Acai Fruit (Euterpe Oleracea) Dye for Chromovitrectomy in Humans

Summary

Our research group tested the toxicity of different dye concentrations extracted from the acai fruit using a rabbit model. The dye extracted from the acai fruit in concentrations of 10% and 25% was found to be safe for vitreoretinal surgery. This initial research represented the landmark research for testing this alternative vital dye in a clinical research in humans.

The aim of the present clinical trial in humans will be to test the applicability of the acai dye in the identification of the posterior hyaloid and ILM during vitreoretinal surgery in humans.

Conditions

• Epiretinal Membrane
• Macular Hole
• Diabetic Retinopathy

Interventions

OTHER

Acai dye 10%

dye to be used during chromovitrectomy in humans

Sponsors & Collaborators

• Rafael R. Caiado

  collaborator UNKNOWN

• Casa de Saúde São José

  collaborator OTHER

• Acácio Alves Souza Lima-Filho

  collaborator UNKNOWN

• Eduardo Novais

  collaborator UNKNOWN

• Emmerson Badaró

  collaborator UNKNOWN

• André Maia

  collaborator UNKNOWN

• Rita Sinigaglia-Coimbra

  collaborator UNKNOWN

• Sung Eun S. Watanabe

  collaborator UNKNOWN

• Eduardo B. Rodrigues

  collaborator UNKNOWN

• Michel Eid Farah

  collaborator UNKNOWN

• Mauricio Maia

  collaborator UNKNOWN

• Federal University of São Paulo

  lead OTHER

Principal Investigators

• Mauricio Maia · Federal University of São Paulo UNIFESP

Study Design

Allocation

RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-02-29

Primary Completion

2016-11-30

Completion

2017-05-31

Countries

• Brazil

Study Locations