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Titrated Quantitative Conjunctival Provocation Test (tqCPT)

NCT02690740 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2016-02-24

No results posted yet for this study

Summary

The clinical relevance of an allergen-specific sensitization is proven e.g., by allergen challenge tests in clinical routine. Several protocols for different challenge tests such as nasal (NPT), bronchial (BPT) or conjunctival provocation test (CPT) have been proposed. Beneath others, the CPT is broadly used in both clinical trials and routine because of its feasibility.

However, there is no internationally harmonized standard regarding the clinical interpretation of CPT results as well as a lack of validation of a specific outcome score. Therefore, this trial aims to investigate and validate a new scoring system for CPT results in order to provide this test as a useful method in future clinical trials.

Conditions

  • Allergic Rhinitis

Interventions

OTHER

(diagnostic) conjunctival provocation test with solution: ALK 100, 1.000, 10.000, 20.000, 50.000 and 100.000 SQ-U/ml

see information in "arm/group descriptions"

Sponsors & Collaborators

  • University Hospital of Cologne

    collaborator OTHER

  • Zentrums für Rhinologie und Allergologie Wiesbaden

    lead OTHER

Principal Investigators

  • Oliver Pfaar, Prof.Dr. · Allergy Center Wiesbaden, Germany

  • Ludger Klimek, Prof. Dr. · Allergy Center Wiesbaden, Germany

  • Dan Philipp Claßen · Allergy Center Wiesbaden, Germany

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
67 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-12-31
Primary Completion
2013-03-31
Completion
2013-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02690740 on ClinicalTrials.gov