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Monitoring of Biomarkers by Portable Breath Gas Sensors: an Exploratory Study

NCT02685241 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2019-10-18

No results posted yet for this study

Summary

Breath analysis is a non-invasive procedure to detect and monitor diseases and it is particularly attractive for patients who have to routinely check biomarkers, such as diabetics (blood glucose) or end-stage renal disease patients (creatinine). Preliminary data in a small study with healthy subjects showed a high correlation between blood glucose levels and acetone. Therefore, the objective of this study is to correlate biomarkers (glucose level and creatinine, respectively) with the corresponding target breath components (acetone and NH3, respectively) detected by portable gas sensors in the general population and to assess possible predictive models for biomarker estimations from the corresponding target breath component and predictive models to estimate abnormal biomarker concentrations.

Conditions

  • General Population

Sponsors & Collaborators

  • Swiss Federal Institute of Technology

    collaborator OTHER

  • University of Zurich

    lead OTHER

Principal Investigators

  • Malcolm Kohler, MD · University of Zurich

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2019-10-31
Completion
2019-10-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02685241 on ClinicalTrials.gov