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Reno-protective Effect of Brain Cooling in Newborn With Hypoxia

NCT02683915 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2018-04-03

No results posted yet for this study

Summary

This study aims to determine the effect of therapeutic hypothermia on reducing AKI in term and late-preterm infants with hypoxic ischemic encephalopathy as estimated by measurment of serum(s) neutrophil gelatinase-associated lipocalin(NGAL) and serum (s) cystatin-C.

Conditions

  • Hypoxic Ischemic Encephalopathy

Interventions

PROCEDURE

Therapeutic hypothermia

Infants in cooled group will be fitted a cooling cap (Olympic Medical Cool Care System, Olympic Medical) around the head for 72 h. infants will be nursed under a radiant overhead heater, which is servo-controlled to the infant's abdominal skin temperature and adjusted to maintain the rectal temperature at 33.5-34.5ºC. At the end of the 72 h cooling period, the infants will be slowly rewarmed at no more than 0•5ºC /h until their temperature become within normal temperature range (36.5-37.5ºC).

Sponsors & Collaborators

  • Mansoura University Children Hospital

    lead OTHER

Eligibility

Min Age
30 Minutes
Max Age
24 Hours
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02683915 on ClinicalTrials.gov