A Study to Investigate the Effect of MT-8554 on the Pharmacokinetics of Simvastatin and Rosuvastatin in Healthy Subjects
NCT02675309 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2025-12-22
Summary
The purpose of this study is to investigate the effect of MT-8554 on the pharmacokinetics of simvastatin and rosuvastatin in healthy subjects.
Conditions
- Healthy
Interventions
- DRUG
-
MT-8554
- DRUG
-
rosuvastatin
- DRUG
-
simvastatin
Sponsors & Collaborators
-
Tanabe Pharma Corporation
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-02-29
- Primary Completion
- 2016-03-31
- Completion
- 2016-03-31
Countries
- United Kingdom
More Related Trials
-
A Study to Investigate the Interaction of GSK1292263 With Rosuvastatin and Simvastatin in Healthy Subjects
NCT01101568 ·Status: COMPLETED ·Phase: PHASE1
-
Investigating the Pharmacokinetic Drug Interactions Between Rosuvastatin and Ezetimibe
NCT02127320 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Drug Interaction Between CKD-519 and Rosuvastatin in Healthy Male Subjects
NCT03175835 ·Status: COMPLETED ·Phase: PHASE1
-
IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin
NCT00654446 ·Status: COMPLETED ·Phase: PHASE3
-
A Multicenter Randomized Parallel-group Study to Investigate the Efficacy of a Combination of Rosuvastatin and Fenofibrate in the Patients With Diabetes or Atherosclerotic Vascular Diseases With Metabolic Syndrome
NCT00965315 ·Status: AVAILABLE
-
to Investigate the Pharmacokinetic Interactions and Safety Between Rosuvastatin and Ezetimibe in Healthy Male Volunteers
NCT02289430 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of PF-06651600 Effect on Rosuvastatin Pharmacokinetics in Healthy Participants
NCT04092595 ·Status: COMPLETED ·Phase: PHASE1
-
Study of PF-04965842 Effect on Rosuvastatin Pharmacokinetics in Healthy Participants
NCT03806101 ·Status: COMPLETED ·Phase: PHASE1
-
Safety Study to Evaluate the Effects of Mild and Moderate Renal Impairment on the Pharmacokinetics of ABT-335 and Rosuvastatin When Administered Concomitantly
NCT00585143 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia
NCT01420549 ·Status: COMPLETED ·Phase: PHASE3
-
Registry On Efficacy and Safety Of Rosuvastatin, and Atorvastatin and Simvastatin In Hypercholesterolaemia
NCT01352897 ·Status: COMPLETED
-
A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833)
NCT02748057 ·Status: COMPLETED ·Phase: PHASE3
-
Assess the Pharmacokinetics of Rosuvastatin and Simvastatin When Administered Alone or in Combination With Fostamatinib
NCT01725230 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and Rosuvastatin in Healthy Male Subjects
NCT02704702 ·Status: COMPLETED ·Phase: PHASE1
-
Genome-wide Analysis of Lipid-lowering Efficacy and Drug Level of Simvastatin and Rosuvastatin
NCT04921657 ·Status: COMPLETED
-
Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart Disease
NCT00329160 ·Status: COMPLETED ·Phase: PHASE4
-
Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998)
NCT05154123 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics and Drug Interaction Study Between Rosuvastatin and CS-866 in Healthy Male Volunteers
NCT01415466 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia.
NCT01982461 ·Status: UNKNOWN ·Phase: NA
-
Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)
NCT00862251 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet
NCT02963116 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Crestor (Rosuvastatin) on Lipid Levels in Patients With Metabolic Syndrome
NCT00815659 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Investigate the Effect of Rosuvastatin (CRESTOR®) on High Density Lipoprotein Kinetics in Patients With the Metabolic Syndrome
NCT00240305 ·Status: COMPLETED ·Phase: PHASE3
-
Study of no Pharmacokinetic Interaction Between Rosuvastatin 20mg and Ezetimibe10mg, Fixed Dose vs Individual Components
NCT04895059 ·Status: COMPLETED ·Phase: PHASE1
-
Investigation of Pharmacokinetic Interaction Between Rosuvastatin and Olmesartan in Healthy Male Volunteers
NCT01831479 ·Status: COMPLETED ·Phase: PHASE1