A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors
NCT02667873 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 72
Last updated 2025-02-10
Summary
Study SL-801-0115 is a dose-escalation study evaluating multiple doses and schedules of orally administered SL-801 in participants with advanced solid tumors.
Conditions
Interventions
- DRUG
-
SL-801
SL-801 is a small-molecule inhibitor of the nuclear export protein Exportin-1 (XPO1).
Sponsors & Collaborators
-
Stemline Therapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-02-23
- Primary Completion
- 2021-10-06
- Completion
- 2021-10-13
Countries
- United States
Study Locations
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