SL-401 in Combination With Pomalidomide and Dexamethasone in Relapsed or Relapsed and Refractory Multiple Myeloma
NCT02661022 · Status: TERMINATED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 9
Last updated 2024-04-17
Summary
A Phase 1/2, Open Label Study of SL-401 in Combination with Pomalidomide and Dexamethasone In Relapsed and Refractory Multiple Myeloma
Conditions
Interventions
- DRUG
-
SL-401 7 µg/kg/day
SL-401 7 µg/kg/day in combination with pom/dex
- DRUG
-
SL-401 9 µg/kg/day
SL-401 9 µg/kg/day in combination with pom/dex
Sponsors & Collaborators
-
Stemline Therapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2019-12-31
- Completion
- 2019-12-31
Countries
- United States
Study Locations
More Related Trials
-
Pomalidomide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT01212952 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combination Study of Pomalidomide, Marizomib, and Low-Dose Dexamethasone in Relapsed and Refractory Multiple Myeloma
NCT02103335 ·Status: COMPLETED ·Phase: PHASE1
-
Pomalidomide (POM) in Combination With Low Dose Dexamethasone (LD-Dex) in Patients With Relapsed or Refractory Multiple Myeloma
NCT01632826 ·Status: APPROVED_FOR_MARKETING
-
Efficacy and Toxicity Study of Pomalidomide and Dexamethasone in Patients Who Have Relapsed After Exposure to Lenalidomide and Bortezomib
NCT02158702 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of the Efficacy and Safety of Pomalidomide Capsules Combined With Low-Dose Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma
NCT05236621 ·Status: UNKNOWN ·Phase: PHASE3
-
Study of Pomalidomide, Cyclophosphamide, Dexamethasone in Relapsed/Refractory Multiple Myeloma
NCT02176213 ·Status: COMPLETED ·Phase: PHASE2
-
Pomalidomide or Lenalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma Previously Treated With Lenalidomide
NCT01794039 ·Status: COMPLETED ·Phase: PHASE2
-
MTD, Safety, and Efficacy of Pomalidomide (CC-4047) Alone or With Low-dose Dexamethasone in Patients With Relapsed and Refractory Multiple Myeloma
NCT00833833 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study to Determine the Maximum Tolerated Dose for the Combination of Pomalidomide, Bortezomib and Low-Dose Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma
NCT01497093 ·Status: COMPLETED ·Phase: PHASE1
-
Pomalidomide and Dexamethasone Effects in Multiple Myeloma Patients With Del 17p or t (4;14)
NCT01745640 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Study of Reduced-dose Pomalidomide and Cyclophosphamide Combined With Dexamethasone in the Treatment of Patients With Debilitating RRMM
NCT06255847 ·Status: RECRUITING ·Phase: PHASE2
-
Pomalidomide in Combination With Low-dose Dexamethasone or Pomalidomide in Combination With Low-dose Dexamethasone and Daratumumab in Subjects With Relapsed or Refractory Multiple Myeloma Following Lenalidomide-based Therapy in the First or Second Line Setting
NCT01946477 ·Status: COMPLETED ·Phase: PHASE2
-
Bendamustine + Pomalidomide + Dex in R/R Multiple Myeloma
NCT01754402 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study Comparing QLS32015 Monotherapy Versus Pomalidomide, Dexamethasone (Pd) or Selinexor, Dexamethasone (Sd) in Participants With Relapsed or Refractory Multiple Myeloma
NCT07138209 ·Status: RECRUITING ·Phase: PHASE3
-
Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma
NCT01522872 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Phase 3, Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Pomalidomide in Combination With Low-Dose Dexamethasone Versus High-Dose Dexamethasone in Subjects With Refractory Multiple Myeloma or Relapsed and Refractory Multiple Myeloma and Companion Study
NCT01311687 ·Status: COMPLETED ·Phase: PHASE3
-
Pomalidomide, Dexamethasone, and Filgrastim-sndz in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT01946152 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
CC-4047 and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Amyloidosis
NCT00558896 ·Status: COMPLETED ·Phase: PHASE2
-
Pomalidomide/Cyclophosphamide/Dexamethasone in Relapse Refractory Myeloma: Safety Profile in Mexicans
NCT03601624 ·Status: UNKNOWN ·Phase: PHASE2
-
CC-5013 Plus Dexamethasone Versus Dexamethasone Alone in Previously Treated Subjects With Multiple Myeloma
NCT00056160 ·Status: COMPLETED ·Phase: PHASE3
-
Selinexor, Pomalidomide, and Dexamethasone With or Without Carfilzomib for the Treatment of Patients With Relapsed Refractory Multiple Myeloma, The SCOPE Trial
NCT04764942 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
IFM2009-02-Pomalidomide and Dexamethasone Phase 2 Myeloma
NCT01053949 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Ixazomib, Given With Dexamethasone in Adults With Multiple Myeloma
NCT03170882 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Pomalidomide and Dexamethasone in RRMM Patients With Renal Insufficiency
NCT02045017 ·Status: COMPLETED ·Phase: PHASE2
-
Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular Lymphoma
NCT01722305 ·Status: COMPLETED ·Phase: PHASE1