A Study of the Efficacy and Safety of VX-150 in Subjects With Osteoarthritis of the Knee
NCT02660424 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 124
Last updated 2020-09-30
Summary
The Primary objective of this study is to evaluate the efficacy of VX-150 in the treatment of osteoarthritis pain
Conditions
Interventions
- DRUG
-
VX-150
- DRUG
Sponsors & Collaborators
-
Vertex Pharmaceuticals Incorporated
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 40 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-12-31
- Primary Completion
- 2016-08-31
- Completion
- 2016-09-30
Countries
- United States
Study Locations
More Related Trials
-
A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain
NCT03660943 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects
NCT02536833 ·Status: COMPLETED ·Phase: PHASE2
-
53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee
NCT06865079 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of the Efficacy and Safety of MEDI7352 in Participants With Painful Osteoarthritis of the Knee
NCT04675034 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee
NCT04129944 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees
NCT01925261 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis Knee Pain
NCT03081806 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Evaluating the Safety and Efficacy of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis
NCT03122860 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 1, Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SM04690 in Moderate to Severe Knee Osteoarthritis (OA)
NCT02095548 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis
NCT02067611 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Safety, Tolerability, Preliminary Efficacy of Intra-articular LNA043 Injections in Patients With Articular Cartilage Lesions and Knee Osteoarthritis.
NCT03275064 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Intra-articular DLX105 Applied to Patients With Severely Painful Osteoarthritis of the Knee
NCT00819572 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee
NCT01111045 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis
NCT07308834 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Etoricoxib in the Treatment of Osteoarthritis (MK-0663-007)
NCT00242489 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate the Efficacy and Safety of Intra-articular DA-5202 in Patients With Osteoarthritis of the Knee
NCT02554240 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 3 Study to Evaluate the Efficacy and Safety of Resiniferatoxin for Pain Due to Osteoarthritis of the Knee
NCT04044742 ·Status: WITHDRAWN ·Phase: PHASE3
-
Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo
NCT04349956 ·Status: TERMINATED
-
A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis
NCT02087904 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Celecoxib Versus Placebo in the Treatment of Patients With Osteoarthritis of the Knee Who Were Unresponsive to Naproxen and Ibuprofen
NCT00640627 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate the Efficacy and Safety of EP-104IAR in Patients With Osteoarthritis of the Knee
NCT04120402 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study Looking at Moderate to Severe Osteoarthritis Knee Pain
NCT00394563 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of ATB-346 Versus Placebo in Osteoarthritis Patients
NCT03978208 ·Status: COMPLETED ·Phase: PHASE2
-
Preliminary Evaluation of Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Osteoarthritic Pain
NCT03282149 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis
NCT04886258 ·Status: COMPLETED ·Phase: PHASE2