Study of Induction of Hypothyroxinemia Adjunct to Conventional Therapies in GBM Patients
NCT02654041 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2018-03-22
Summary
The objective of the study is to assess the safety and efficacy of treatment with hypothyroxinemia adjunct to conventional therapies in GBM patients.
Conditions
- Glioblastoma Multiforme (GBM)
Interventions
- DRUG
-
Combined T3 and Methimazole treatment
Oral administration of T3 and Methimazole
Sponsors & Collaborators
-
Tel-Aviv Sourasky Medical Center
collaborator OTHER_GOV -
Musli Thyropeutics Ltd.
lead INDUSTRY
Principal Investigators
-
Deborah T Blumenthal, MD · Tel-Aviv Medical Center, Israel
Study Design
- Allocation
- NA
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-03-31
- Primary Completion
- 2017-06-30
- Completion
- 2017-06-30
Countries
- Israel
Study Locations
More Related Trials
-
Recombinant Human Thyroid Stimulating Hormone for Radioiodine 131I Treatment
NCT06405217 ·Status: RECRUITING ·Phase: NA
-
A Prospective Evaluation of Microwave Ablation (MWA) in the Treatment of Relapsed Graves' Disease
NCT06506149 ·Status: RECRUITING ·Phase: NA
-
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
NCT06727604 ·Status: RECRUITING ·Phase: PHASE2
-
Evaluation of Optimal Time of Methimazole Discontinuation Before Radio-iodine Therapy in Hyperthyroid Grave's Patients
NCT01560299 ·Status: COMPLETED ·Phase: NA
-
The Safety and Effectiveness of rhTSH in Radioiodine Treatment for Patients With Differentiated Thyroid Cancer.
NCT04447183 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Association Between Cancer Cells and Normal Versus (Vs.) Low Levels of Thyroid Hormones in the Serum
NCT01153945 ·Status: WITHDRAWN
-
A Retrospective Observational Study Comparing Two Different Treatment Options in Thyroid Cancer Patients With T4 Tumours
NCT01736163 ·Status: COMPLETED
-
Combined Levothyroxine/Liothyronine Supplementation in Hypothyroid Patients With Brain Tumors
NCT00488644 ·Status: TERMINATED ·Phase: NA
-
A Clinical Study of Hyperthyroidism in Children
NCT06570967 ·Status: RECRUITING
-
Comparison of the Safety and Successful Ablation of Thyroid Remnant in Post-thyroidectomized Euthyroid Patients (i.e. Patients Administered Thyrogen) Versus Hypothyroid Patients (no Thyrogen) Following 131I Administration
NCT00196729 ·Status: COMPLETED ·Phase: PHASE3
-
Block-replacement Therapy During Radioiodine Therapy
NCT00150124 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of the Efficacy and Safety of rhTSH as An Adjunctive Diagnostic Tool in Differentiated Thyroid Cancer Patients Who Had Been Thyroidectomized Vs. Patients Who After Thyroid Hormone Withdrawal
NCT04971473 ·Status: COMPLETED ·Phase: PHASE3
-
Study of the Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Thyroid Cancer
NCT00094055 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Recombinant Human Thyroid Stimulating Hormone for Adjuvant Diagnosis in Patients With Locally Advanced/Metastatic Differentiated Thyroid Cancer
NCT06431620 ·Status: RECRUITING ·Phase: NA
-
Recombinant Thyrotropin PET-CT Fusion Scanning in Thyroid Cancer
NCT00181168 ·Status: COMPLETED ·Phase: PHASE2
-
A New Study to Follow-up Thyroid Cancer Patients Who Participated in a Previous Study, Which Compared the Success of Destruction of the Thyroid Remnant Using Standard Treatment or Thyrogen.
NCT00295763 ·Status: COMPLETED ·Phase: PHASE3
-
Follow up for Patients With Thyroid Cancer Planed for Radioiodine Scan or Treatment
NCT03624751 ·Status: ACTIVE_NOT_RECRUITING
-
rhTSH, Radioiodine Uptake and Goiter Reduction Following 131I Therapy in Patients With Benign Nontoxic Nodular Goiter
NCT00275171 ·Status: COMPLETED ·Phase: PHASE2
-
99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients
NCT03065218 ·Status: TERMINATED ·Phase: PHASE4
-
Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine Supplementation
NCT00360074 ·Status: COMPLETED ·Phase: PHASE4
-
Desiccated Thyroid Extract Combined With Levothyroxine for TSH Suppression Therapy in DTC
NCT07239674 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Clinical Trial of Dose-tolerance, Pharmacokinetics and Iodine Uptake For rhTSH In Post-thyroidectomized Patients
NCT04137185 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
An Assessment of the Occurrence of Hypothyroidism in Patients Treated With RAI for Hyperthyroidism.
NCT04663451 ·Status: UNKNOWN
-
Graves' Disease Remission Study: MycoMeth Combo
NCT06068179 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
TSH Suppression During Radiotherapy on Thyroid Site to Prevent Iatrogenic Hypothyroidism in Pediatric Cancer Patients
NCT05316922 ·Status: RECRUITING ·Phase: PHASE3