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Nucleotide Polymorphism in ARDS Outcome

NCT02644798 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 105

Last updated 2022-03-15

No results posted yet for this study

Summary

Acute respiratory distress syndrome (ARDS) is characterized by increased pulmonary vascular permeability and reduced aerated lung tissue. With an extremely high hospital mortality among 35 - 46%, current therapeutic strategies to increase ARDS survival are still limited. Advances in etiology and pathology of ARDS are urging. Numerous genetic variants were identified associated with ARDS outcome. By whole-exome sequencing association study, our goal was to explore the associations between genetic variants and ARDS outcome.

Conditions

  • ARDS

Interventions

OTHER

Baseline-recorded data recorded

Baseline-recorded data recorded. Peripheral blood samples were drawn.

Sponsors & Collaborators

  • Southeast University, China

    lead OTHER

Principal Investigators

  • Jingyuan Xu, M.D. · Southeast University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-01
Primary Completion
2016-12-01
Completion
2017-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02644798 on ClinicalTrials.gov