MedTrace Logo

Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults

NCT02636803 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL

Last updated 2019-08-15

No results posted yet for this study

Summary

The aim of this study is to provide data on the efficacy of oxfendazole against Trichuris trichiura at different doses in comparison to the standard single 400 mg dose of albendazole. In addition, the study will provide data on oxfendazole efficacy against other common nematodes encountered in man (Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma duodenalis, Necator americanus).

Conditions

  • Helminthiasis

Interventions

DRUG

oxfendazole

group receives a single dose of oxfendazole at 6 or 30 mg/kg or three 6 mg/kg doses

DRUG

albendazole

group receives one 400 mg dose of albendazole

Sponsors & Collaborators

  • Universidad Peruana Cayetano Heredia

    collaborator OTHER

  • Johns Hopkins Bloomberg School of Public Health

    lead OTHER

Principal Investigators

  • Robert H Gilman, MD · Johns Hopkins Bloomberg School of Public Health

  • Hector H Garcia, MD, PhD · Universidad Peruana Cayetano Heredia

  • Richard J Horton, MB BChir, MRCGP, FFPM · Tropical Projects

  • Armando E Gonzalez, DVM, PhD · National University of San Marcos, Peru

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
FACTORIAL

Eligibility

Min Age
16 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-30
Primary Completion
2020-08-31
Completion
2021-02-28
FDA Drug
Yes

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02636803 on ClinicalTrials.gov