MedTrace Logo

Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial Infarction

NCT02627950 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 138

Last updated 2019-08-08

No results posted yet for this study

Summary

The current prospective, randomized, controlled MonAMI trial aims to systematically examine the effects of morphine on the platelet inhibitory effects of the orally administered platelet inhibitor ticagrelor in patients with acute myocardial infarction. In addition, the potential positive or negative effects of MCP in combination with morphine on platelet inhibition will be studied.

Conditions

  • Acute Myocardial Infarction

Interventions

DRUG

Morphinhydrochloricum

5 mg morphine intravenously

DRUG

Metoclopramide

10 mg MCP intravenously

DRUG

Ticagrelor

180 mg ticagrelor orally

DRUG

Isotonic sodium chloride

10 ml NaCl 0.9% intravenously

Sponsors & Collaborators

  • University of Luebeck

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-12-31
Primary Completion
2018-10-31
Completion
2018-10-31

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02627950 on ClinicalTrials.gov