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A Single-Center, Exploratory Study to Analyze the Dynamics of Skin Microflora Following Exposure to Surfactants

NCT02615912 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2016-09-28

No results posted yet for this study

Summary

The purpose of this study is to understand the changes in skin microflora, skin barrier function, and skin biochemical constituents in response to direct contact with model surfactants used in personal care articles. The results from this study will provide insights into the complex interaction between the skin microbiome and the epidermis after exposure to surfactants.

Conditions

  • Dermatitis

Interventions

OTHER

PEG-40 Hydrogenated Castor Oil (Tagat CH40, Evonik) 1.5%

OTHER

Lauryl glucoside (Plantacare® 1200UP, BASF) 1.5%

OTHER

Sorbitan palmitate (SPANTM 40 (powder), Croda) 1.5%

OTHER

Silwet* DA-63 (Momentive) 1.5%

OTHER

Sodium lauryl sulfate (Sigma Aldrich) 1.0%

OTHER

Water (control)

Sponsors & Collaborators

  • Kimberly-Clark Corporation

    lead INDUSTRY

Principal Investigators

  • Barry Reece, MBA · RCTS, Inc.

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2015-12-31
Completion
2016-02-29

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02615912 on ClinicalTrials.gov