Clinical Trial of the Use of Ketamine in Treatment Resistant Depression
NCT02610712 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2016-09-21
Summary
The purpose of this study is to determine the efficacy of the use of intravenous low-dose ketamine in the treatment of treatment-resistant depression (TRD), as well as the changes in Glutamate neurotransmission and inflammatory serum markers.
Conditions
- Depressive Disorder, Treatment-Resistant
Interventions
- DRUG
Sponsors & Collaborators
-
National Institute of Neurology and Neurosurgery, Mexico
lead OTHER
Principal Investigators
-
Rodrigo Pérez-Esparza, MD · National Institute of Neurology and Neurosurgery, Mexico
-
Jesús Ramírez-Bermúdez, MD, MSc · National Institute of Neurology and Neurosurgery, Mexico
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-05-31
- Primary Completion
- 2017-12-31
Countries
- Mexico
Study Locations
More Related Trials
-
Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression
NCT02522377 ·Status: COMPLETED ·Phase: NA
-
Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder
NCT01667926 ·Status: COMPLETED ·Phase: NA
-
Ketamine Plus Lithium in Treatment-Resistant Depression
NCT01880593 ·Status: COMPLETED ·Phase: PHASE2
-
Ketamine Associated ACC GABA and Glutamate Change and Depression Remission:
NCT03573349 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Ketamine for Treatment Resistant Late-Life Depression
NCT02556606 ·Status: COMPLETED ·Phase: PHASE3
-
Double-Blind Trial of Ketamine Therapy Plus or Minus Naltrexone in Treatment Resistant Depression (TRD)
NCT02911597 ·Status: COMPLETED ·Phase: PHASE1
-
Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)
NCT01920555 ·Status: COMPLETED ·Phase: PHASE2
-
Ketamine as an Alternative Treatment to ECT in Major Depressive Disorder
NCT02659085 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
The UTHealth Ketamine Project
NCT02882711 ·Status: TERMINATED ·Phase: PHASE2
-
Intravenous Ketamine for Treatment-Resistant Depression
NCT06668571 ·Status: RECRUITING ·Phase: PHASE2
-
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
NCT07247006 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study to Decrease Suicidal Thinking Using Ketamine
NCT02418702 ·Status: WITHDRAWN ·Phase: PHASE3
-
Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression
NCT02360280 ·Status: COMPLETED ·Phase: PHASE2
-
Ketamine in the Treatment of Depression
NCT01558063 ·Status: COMPLETED ·Phase: PHASE2
-
Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression
NCT04239963 ·Status: COMPLETED
-
ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)
NCT03113968 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Ketamine for Depression Relapse Prevention Following ECT
NCT02414932 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)
NCT04663321 ·Status: TERMINATED ·Phase: PHASE2
-
Cognitive Training as an Adjunct to Ketamine in Real-world Clinics
NCT06526078 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Optimization of IV Ketamine for Treatment Resistant Depression
NCT00768430 ·Status: COMPLETED ·Phase: PHASE2
-
Intravenous Ketamine Effects on Functional Neuroanatomy
NCT04205890 ·Status: WITHDRAWN ·Phase: PHASE1
-
Ketamine Trial for the Treatment of Depression
NCT02401139 ·Status: COMPLETED ·Phase: PHASE1
-
IV Ketamine Vs. in Esketamine for MDD TRD
NCT06488586 ·Status: RECRUITING
-
Repeated Neurocognitive Measurements in Depressed Patients
NCT05991232 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Continuation Ketamine in Major Depression
NCT00548964 ·Status: COMPLETED ·Phase: PHASE1