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Imminently Effect of Interval Training With High Intensity (HIT) After Heart Transplantation

NCT02602834 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19

Last updated 2016-11-10

No results posted yet for this study

Summary

High intensity Interval training (HIT) has repeatedly been documented to have superior positive effects on oxygen uptake and general physical health compared to continuous moderate exercise in healthy individuals and patients with heart disease. Recently, the same effect has been shown in heart transplanted recipients. Which mechanisms that explains this difference is uncertain; the effect can be due to changes in the heart or changes in the peripheral tissue and muscles. To explore these mechanisms the investigators will in this study compare two different exercise modalities, and explore how different biomarkers change in blood, related to exercise.

Conditions

  • Heart Transplantation

Interventions

OTHER

interval training

4 intervals with high intensity on treadmill, and approximately 3 minutes rest between intervals.

OTHER

moderate exercise

30 minutes (moderate intensity) aerobic exercise on treadmill without rest.

Sponsors & Collaborators

  • Norwegian Health Association

    collaborator OTHER

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Lars LG Gullestad, professor · OUS-Oslo university hospital rikshospitalet, cardiology department

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-05-31
Primary Completion
2015-11-30
Completion
2015-11-30

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02602834 on ClinicalTrials.gov