Phase I/II Study of Anti-Mucin1 (MUC1) CAR T Cells for Patients With MUC1+ Advanced Refractory Solid Tumor
NCT02587689 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2016-12-05
Summary
The purpose of this study is to determine whether autologous T cells bearing chimeric antigen receptor that can specifically recognize (Mucin 1) MUC1 is safe and effective for patients with relapsed or refractory solid tumor.
Conditions
- Hepatocellular Carcinoma
- Non-small Cell Lung Cancer
- Pancreatic Carcinoma
- Triple-Negative Invasive Breast Carcinoma
Interventions
- BIOLOGICAL
-
anti-MUC1 CAR T Cells
Sponsors & Collaborators
-
The First People's Hospital of Hefei
collaborator OTHER -
Hefei Binhu Hospital
collaborator OTHER -
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Lin Yang, Ph.D. · PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-10-31
- Primary Completion
- 2017-10-31
- Completion
- 2018-10-31
Countries
- China
Study Locations
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