A Cross Sectional Evaluation of the Development in Children Age 4 to 7 Infected or Exposed to HIV From the ANRS 12140 Cohort (Pediacam)

Summary

This study aims to perform a comprehensive neuro-cognitive evaluation of the 4-7 year old children from the Pediacam cohort (ANRS 12140 /12225, NCT02043418). It is expected thereby to provide complementary information to the trials CHER and PREDICT on the long term development of (1) HIV-infected children according to age at ARV initiation and (2) HIV exposed but not infected children, all compared with the control group of children uninfected, unexposed to HIV.

Conditions

• HIV
• HIV-uninfected Children
• Children Exposed to HIV

Interventions

OTHER

HIV-infected children initiated antiretroviral treatment within the first 7 months of life

All arms will recieve a thourough clinical evaluation : Global motor development (Touwen test), global cognitive development (K-ABC II test), visual (Log Mar Char) and hearing (full ear nose and throat examination) impediments as well as a questionnaire concerning socioeconomic situation, medical history of the child and mother, and HIV treatment and follow up information.

Sponsors & Collaborators

• Centre Pasteur du Cameroun

  collaborator OTHER

• Hopital Universitaire Robert-Debre

  collaborator OTHER

• Institut de Recherche pour le Developpement

  collaborator OTHER_GOV

• Centre Mère et Enfant de la Fondation Chantal Biya

  collaborator OTHER

• Hospital General De Douala

  collaborator OTHER

• Centre Hospitalier D'essos

  collaborator OTHER

• Inserm U1018, Equipe 4 VIH & IST

  collaborator UNKNOWN

• ANRS, Emerging Infectious Diseases

  lead OTHER_GOV

Study Design

Allocation

NON_RANDOMIZED

Purpose

SCREENING

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

4 Years

Max Age

7 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-12-31

Primary Completion

2016-10-31

Completion

2016-12-31

Countries

• Cameroon

Study Locations