Trial Outcomes & Findings for Stand & Move at Work (NCT NCT02566317)

Results Overview

Measured via 7d of activPAL accelerometry (value at 12 months minus value at baseline)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

630 participants

Primary outcome timeframe

1 year

Results posted on

2019-10-11

Participant Flow

Unit of analysis: Worksites

Participant milestones

Participant milestones
Measure	MOVE+ A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace. Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace	STAND+ Move intervention (A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace) plus the installation of a sit-stand workstation. Sit-Stand workstation: Installation of a sit-stand desk at work Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace
Overall Study STARTED	276 12	354 12
Overall Study COMPLETED	247 12	292 12
Overall Study NOT COMPLETED	29 0	62 0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Stand & Move at Work

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	MOVE+ n=276 Participants A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace. Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace	STAND+ n=354 Participants Move intervention (A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace) plus the installation of a sit-stand workstation. Sit-Stand workstation: Installation of a sit-stand desk at work Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace	Total n=630 Participants Total of all reporting groups
Age, Categorical <=18 years	0 Participants n=99 Participants	0 Participants n=107 Participants	0 Participants n=206 Participants
Age, Categorical Between 18 and 65 years	276 Participants n=99 Participants	354 Participants n=107 Participants	630 Participants n=206 Participants
Age, Categorical >=65 years	0 Participants n=99 Participants	0 Participants n=107 Participants	0 Participants n=206 Participants
Age, Continuous	44 years STANDARD_DEVIATION 11 • n=99 Participants	47 years STANDARD_DEVIATION 11 • n=107 Participants	45 years STANDARD_DEVIATION 11 • n=206 Participants
Sex: Female, Male Female	173 Participants n=99 Participants	296 Participants n=107 Participants	469 Participants n=206 Participants
Sex: Female, Male Male	103 Participants n=99 Participants	58 Participants n=107 Participants	161 Participants n=206 Participants
Race/Ethnicity, Customized Non-Hispanic White	250 Participants n=99 Participants	239 Participants n=107 Participants	489 Participants n=206 Participants
Race/Ethnicity, Customized Hispanic	30 Participants n=99 Participants	57 Participants n=107 Participants	87 Participants n=206 Participants
Race/Ethnicity, Customized Non-Hispanic Black	6 Participants n=99 Participants	20 Participants n=107 Participants	26 Participants n=206 Participants
Race/Ethnicity, Customized Non-Hispanic Asian	17 Participants n=99 Participants	15 Participants n=107 Participants	32 Participants n=206 Participants
Race/Ethnicity, Customized Other/Multiracial/Unknown	18 Participants n=99 Participants	23 Participants n=107 Participants	41 Participants n=206 Participants
Region of Enrollment United States	276 participants n=99 Participants	354 participants n=107 Participants	630 participants n=206 Participants

PRIMARY outcome

Timeframe: 1 year

Population: Among those who completed the study in the MOVE+ arm (n=247), 16 did not have sufficient valid workdays and 7 were missing covariates. Among those who completed the study in the STAND+ arm (n=292), 17 did not have sufficient valid workdays and 12 were missing covariates.

Measured via 7d of activPAL accelerometry (value at 12 months minus value at baseline)

Outcome measures

Outcome measures
Measure	MOVE+ n=224 Participants A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace. Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace	STAND+ n=263 Participants Move intervention (A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace) plus the installation of a sit-stand workstation. Sit-Stand workstation: Installation of a sit-stand desk at work Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace
Mean Change in Light-intensity Physical Activity at Work From Baseline to 12 Months	-0.2 Mean change, minutes per 8hr workday Interval -2.4 to 2.1	2.0 Mean change, minutes per 8hr workday Interval -0.1 to 4.2

PRIMARY outcome

Timeframe: 1 year

Population: Among those who completed the study in the MOVE+ arm (n=247), 16 did not have sufficient valid workdays and 7 were missing covariates. Among those who completed the study in the STAND+ arm (n=292), 17 did not have sufficient valid workdays and 12 were missing covariates.

Measured via 7d of activPAL accelerometry (value at 12 months minus value at baseline)

Outcome measures

Outcome measures
Measure	MOVE+ n=224 Participants A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace. Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace	STAND+ n=263 Participants Move intervention (A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace) plus the installation of a sit-stand workstation. Sit-Stand workstation: Installation of a sit-stand desk at work Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace
Mean Change in Sitting Time at Work From Baseline to 12 Months	6.8 Mean Change, minutes per 8h workday Interval -4.3 to 17.8	-52.4 Mean Change, minutes per 8h workday Interval -62.9 to -42.0

SECONDARY outcome

Timeframe: 1 year

Population: In MOVE+ (n=247), 10 did not attend posttest visit, 3 were unable to perform a blood draw, 19 refused blood draw, 3 had an insufficent sample, and 8 were missing covariates. In STAND+ (n=292), 16 did not attend posttest visit, 3 were unable to perform a blood draw, 27 refused blood draw, 3 had an insufficent sample, and 5 were missing covariates.

Clustered metabolic risk score (fasting glucose, insulin, triglycerides, HDL-cholesterol, blood pressure); value at 12 months minus value at baseline; higher scores indicate better outcome. The Z-score for each component (fasting glucose, insulin, triglycerides, HDL-cholesterol, blood pressure) based on the baseline mean and standard deviation of the entire group was computed and summed for each participant (HDL z-score was subtracted rather than added). The sum of these z-scores represents the metabolic risk score.

Outcome measures

Outcome measures
Measure	MOVE+ n=204 Participants A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace. Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace	STAND+ n=238 Participants Move intervention (A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace) plus the installation of a sit-stand workstation. Sit-Stand workstation: Installation of a sit-stand desk at work Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace
Clustered Metabolic Risk Score From Baseline to 12 Months	0.02 units on a scale Interval -0.12 to 0.17	-0.15 units on a scale Interval -0.27 to -0.04

OTHER_PRE_SPECIFIED outcome

Timeframe: 1 year

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Matthew Buman, PhD

Arizona State University

Phone: 602-827-2289

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place