Study of LY3023414 for the Treatment of Recurrent or Persistent Endometrial Cancer
NCT02549989 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2023-02-22
Summary
The purpose of this study is to determine the effectiveness of LY3023414 in treating the participants type of cancer and to determine the types and severity of side effects caused by treatment with LY3023414.
Conditions
- Endometrial Cancer
- Recurrent Endometrial Cancer
Interventions
- DRUG
-
LY3023414
Enrolled patients will take LY3023414 200 mg orally twice a day. Each cycle will be 21 days in duration. Patients will receive study treatment until disease progression, intolerable toxicity, elective withdrawal from the study, study completion, or study termination
Sponsors & Collaborators
- collaborator INDUSTRY
-
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Vicky Makker, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-09-30
- Primary Completion
- 2022-03-23
- Completion
- 2022-03-23
Countries
- United States
Study Locations
More Related Trials
-
Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer
NCT01225887 ·Status: COMPLETED ·Phase: PHASE2
-
Ixabepilone in Treating Patients With Recurrent or Persistent Endometrial Cancer
NCT00095979 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of GDC-0980 in the Treatment of Recurrent or Persistent Endometrial Carcinoma
NCT01455493 ·Status: COMPLETED ·Phase: PHASE2
-
Liposomal Doxorubicin in Treating Patients With Advanced or Recurrent Endometrial Cancer
NCT00005861 ·Status: COMPLETED ·Phase: PHASE2
-
Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer
NCT02912572 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Pembrolizumab With Lenvatinib in Women With Advanced Uterine Carcinosarcoma
NCT05147558 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Chemotherapy Treatment for Patients With Ovarian Cancer
NCT00428610 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial Carcinosarcoma
NCT05156268 ·Status: COMPLETED ·Phase: PHASE2
-
A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck
NCT01059643 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Second Look Laparoscopy (SLL) in People With Ovarian Cancer Who Have Completed Their First Course of Chemotherapy
NCT06240598 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 1/2a Evaluation of AL3818 in Subjects With Recurrent or Metastatic Endometrial, Ovarian or Cervical Cancer (AL3818-US-001)
NCT02558348 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer
NCT05691010 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission
NCT00522301 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine in Treating Patients With Recurrent or Refractory Cancer of the Uterus
NCT00003316 ·Status: TERMINATED ·Phase: PHASE2
-
Danazol in Treating Patients With Advanced or Recurrent Endometrial Cancer
NCT00003946 ·Status: COMPLETED ·Phase: PHASE2
-
Pembrolizumab in Ultramutated and Hypermutated Endometrial Cancer
NCT02899793 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
NCT04486352 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Evaluation of Enzastaurin in the Treatment of Persistent or Recurrent Ovarian or Primary Peritoneal Cancer
NCT00420381 ·Status: COMPLETED ·Phase: PHASE2
-
BEZ235 Trial in Patients With Advanced Endometrial Carcinoma
NCT01290406 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study of Durvalumab With or Without Tremelimumab in Endometrial Cancer
NCT03015129 ·Status: COMPLETED ·Phase: PHASE2
-
Pembro/Carbo/Taxol in Endometrial Cancer
NCT02549209 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract
NCT00003334 ·Status: COMPLETED ·Phase: PHASE2
-
Dasatinib in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, Endometrial or Peritoneal Cancer
NCT02059265 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Envafolimab Alone or With Lenvatinib in Patients With Advanced Endometrial Cancer
NCT05112991 ·Status: RECRUITING ·Phase: PHASE2
-
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
NCT05611931 ·Status: RECRUITING ·Phase: PHASE3