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Comparison of Loading Strategies With Antiplatelet Drugs in Patients Undergoing Elective Coronary Intervention

NCT02548611 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 795

Last updated 2020-07-17

No results posted yet for this study

Summary

Use of high loading doses of clopidogrel (antiplatelet drug) just before coronary interventions is associated with improved outcomes after coronary stenting. However the onset of platelet inhibition after clopidogrel loading takes 2 to 4 hours and its action if very variable. A way to overcome this limitation is loading with a more potent antiplatelet drug such as prasugrel. Therefore in the current study the investigators want to compare loading with 60 mg prasugrel (potent antiplatelet drug) and loading with clopidogrel (standard drug) in patients undergoing elective coronary intervention.

Conditions

  • Angina Pectoris

Interventions

DRUG

Prasugrel

see arm description

DRUG

Clopidogrel

see arm description

Sponsors & Collaborators

  • LMU Klinikum

    lead OTHER

Principal Investigators

  • Julinda Mehilli, MD · University Hospital Munich

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2018-08-31
Completion
2018-11-30

Countries

  • Germany
  • Hungary

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02548611 on ClinicalTrials.gov