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Associations of Vitamin D Deficiency and Vitamin D Receptor Polymorphisms With the Risk of Primary Open-angle Glaucoma

NCT02539745 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2016-04-22

No results posted yet for this study

Summary

This study investigated whether vitamin D receptor gene polymorphism is altered in primary open-angle glaucoma subjects carrying the risk allele and vitamin D deficiency is an important factor in the development of glaucoma. Primary open-angle glaucoma patients and age-matched people in the Han population were enrolled. Serum levels of 1a, 25-Dihydroxyvitamin D3 were measured by enzyme-linked immunoabsorbent assay. Vitamin D receptor polymorphic analysis was studied by real-time polymerase-chain reaction high resolution melting analysis.

Conditions

  • Vitamin D Deficiency
  • Primary Open- Angle Glaucoma

Interventions

OTHER

Vitamin D receptor polymorphic analysis

Vitamin D receptor polymorphic analysis was studied by real-time polymerase-chain reaction high resolution melting analysis.

OTHER

Serum levels of 1a, 25-Dihydroxyvitamin D3

Serum levels of 1a, 25-Dihydroxyvitamin D3 were measured by enzyme-linked immunoabsorbent assay.

Sponsors & Collaborators

  • Lv Yingjuan

    lead OTHER

Principal Investigators

  • xiaorong li · Tianjin Medical University Eye Hospital

Eligibility

Min Age
55 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-07-31
Primary Completion
2014-12-31
Completion
2015-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02539745 on ClinicalTrials.gov