Comparison of Efficacy and Safety of Microfracture and Modified Microfracture

Summary

This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture to prove the non-inferiority of the modified microfracture using collagen in patients with cartilage defects in their knees.

Conditions

• Defect of Articular Cartilage
• Osteoarthritis
• Traumatic Arthritis

Interventions

PROCEDURE

Microfracture

simple microfracture

DEVICE

CartiFill

add collagen when doing microfracture

Sponsors & Collaborators

• Sewon Cellontech Co., Ltd.

  lead INDUSTRY

Principal Investigators

• Nam Yong Choi, MD · Catholic University of Korea Saint Paul's Hospital

• Yong In, MD · The Catholic University of Korea

• Chan Woong Moon, MD · The Catholic University of Korea Bucheon St.Mary's Hospital

• Hae Seock Ko, MD · The Catholic University of Korea Vincent's Hospital

• Cheol Hong Jeon, MD · Wonkwang University Hospital

• Seung Back Kang, MD · SMG-SNU Boramae Medical Center

• Ja Young Choi, MD · Seoul National University Hospital

• Myung Koo Kim, MD · Inha University Hospital

• Jae Kyun Jun, MD · Daejeon Sun hospital

• Jae Doo Yoo, MD · Ewha Womans University Mokdong Hospital

• Jung Koo Ha, MD · Inje University

• Jun Ho Wang, MD · Samsung Medical Center

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

15 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-02-28

Primary Completion

2016-01-31

Completion

2017-06-30

Countries

• South Korea

Study Locations