Phase 1 Combination Study of MM-151 With MM-121, MM-141, or Trametinib
NCT02538627 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2017-09-05
Summary
This is a Phase 1 open-label, dose-escalation trial using "3+3" design, evaluating MM-151 co-administration with MM-121, MM-141, and trametinib at varying dose levels.
Conditions
- Colorectal Cancer
- Non-small Cell Lung Cancer
- Squamous Cell Carcinoma of the Head and Neck
Interventions
- DRUG
-
MM-151
MM-151
- DRUG
-
MM-121
MM-121
- DRUG
-
MM-141
MM-141
- DRUG
-
trametinib
trametininb
Sponsors & Collaborators
-
Merrimack Pharmaceuticals
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-08-31
- Primary Completion
- 2016-10-05
- Completion
- 2016-10-05
Countries
- United States
Study Locations
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