MedTrace Logo

The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune Responses

NCT02538211 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 63

Last updated 2017-07-25

No results posted yet for this study

Summary

The purpose of this study is to evaluate if the intestinal microbiota influences rotavirus vaccine immune responses in healthy adult volunteers.

Conditions

  • Rotavirus Infections
  • Intestinal Bacteria Flora Disturbance
  • Reaction - Vaccine Nos
  • Tetanus
  • Streptococcal Pneumonia

Interventions

BIOLOGICAL

Rotavirus vaccine, Tetanus vaccine and Pneumococcal vaccine

All subjects will be given an oral dose of the rotavirus vaccine, RotarixTM, and intramuscular injections of the Tetanus vaccine and Pneumococcal vaccine, Pneumo 23.

Sponsors & Collaborators

Principal Investigators

  • Willem J. Wiersinga, MD, PhD · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2017-01-31
Completion
2017-02-28

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02538211 on ClinicalTrials.gov