HuMax-IL8 (Interleukin8) in Patients With Advanced Malignant Solid Tumors
NCT02536469 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2017-02-03
Summary
A phase Ib, dose escalation, multiple dose trial with HuMax-IL8 in patients with metastatic or unresectable, locally advanced malignant solid tumors.
Conditions
Interventions
- DRUG
-
HuMax-IL8
HuMax-IL8 drug product intended for intravenous infusion. Subjects will be treated every 2 weeks. Every 2 doses (4 weeks) will be considered 1 cycle
Sponsors & Collaborators
-
This trial was conducted previously by Cormorant
collaborator UNKNOWN - lead INDUSTRY
Principal Investigators
-
Bristol-Myers Squibb · Bristol-Myers Squibb
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-08-31
- Primary Completion
- 2016-11-30
- Completion
- 2016-11-30
Countries
- United States
Study Locations
More Related Trials
-
Interleukin-2 Combined With Monoclonal Antibody Therapy in Treating Patients With Kidney, Bladder, or Lung Cancer That Has Not Responded to Previous Treatment
NCT00016237 ·Status: COMPLETED ·Phase: PHASE1
-
Interleukin-21 in Treating Patients With Metastatic or Recurrent Malignant Melanoma
NCT00514085 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers
NCT06840119 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
NHS-IL12 for Solid Tumors
NCT01417546 ·Status: COMPLETED ·Phase: PHASE1
-
Study of IMC-11F8 in Participants With Advanced Solid Tumors
NCT01088464 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of IMC-002 in Patients With Advanced Cancer Failed to Standard Therapy
NCT05276310 ·Status: RECRUITING ·Phase: PHASE1
-
Maytansinoid DM4-Conjugated Humanized Monoclonal Antibody huC242 in Treating Patients With Solid Tumors
NCT00352131 ·Status: COMPLETED ·Phase: PHASE1
-
Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts
NCT01701674 ·Status: COMPLETED ·Phase: NA
-
Interleukin-12 in Treating Patients With Cancer in the Abdomen
NCT00003046 ·Status: COMPLETED ·Phase: PHASE1
-
Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma
NCT04940299 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Continuous Infusion of rhIL-15 for Adults With Advanced Cancer
NCT01572493 ·Status: COMPLETED ·Phase: PHASE1
-
Intratumoral Tilsotolimod, a TLR-9 Agonist, Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers
NCT04270864 ·Status: TERMINATED ·Phase: PHASE1
-
Safety and Efficacy of MIW815 (ADU-S100) +/- Ipilimumab in Patients With Advanced/Metastatic Solid Tumors or Lymphomas
NCT02675439 ·Status: TERMINATED ·Phase: PHASE1
-
Vaccine Therapy and GM-CSF With or Without Low-Dose Aldesleukin in Treating Patients With Stage II, Stage III, or Stage IV Melanoma
NCT00470015 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Trial of Immunotherapy in Patients With Carcinomas Arising From the Renal Medulla
NCT05347212 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Stage IIC-IV Melanoma
NCT00085189 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Therapy and Vaccine Therapy in Treating Patients With Resected Stage III or Stage IV Melanoma
NCT00084656 ·Status: COMPLETED ·Phase: PHASE2
-
The IIT Study of Evaluation of P-IL-2 Single Agent and With Anti-PD-1
NCT05829057 ·Status: RECRUITING ·Phase: PHASE1
-
Humanized 3F8 Monoclonal Antibody (Hu3F8) When Combined With Interleukin-2 in Patients With High-Risk Neuroblastoma and GD2-positive Solid Tumors
NCT01662804 ·Status: COMPLETED ·Phase: PHASE1
-
Safety of Recombinant Human IL-21-expressing Oncolytic Vaccinia Virus Injection (hV01) in Advanced Tumors
NCT05914376 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
NCT05361174 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
OH2 Injection in Combination With HX008 for Melanoma.
NCT04616443 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed
NCT03444753 ·Status: TERMINATED ·Phase: PHASE1
-
Multiple Class I Peptides & Montanide ISA 51 VG w Escalating Doses of Anti-PD-1 ab BMS936558
NCT01176461 ·Status: COMPLETED ·Phase: PHASE1
-
Interleukin-2 Plus Monoclonal Antibody Therapy in Treating Patients With Solid Tumors
NCT00002994 ·Status: COMPLETED ·Phase: PHASE1