MedTrace Logo

MVA85A Aerosol vs Intramuscular Vaccination in Adults With Latent Mycobacterium Tuberculosis (M. tb) Infection

NCT02532036 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 2

Last updated 2020-08-31

Study results available
· View outcomes & findings →

Summary

TB040 is a clinical trial to investigate and compare the effects of a candidate Tuberculosis (TB) vaccine, MVA85A, administered by the aerosol inhaled route and the intramuscular route in healthy adult volunteers who are latently infected with Mycobacterium tuberculosis.

Conditions

Interventions

BIOLOGICAL

Aerosol inhaled MVA85A

BIOLOGICAL

Intramuscular MVA85A

BIOLOGICAL

Intramuscular Saline placebo

BIOLOGICAL

Aerosol inhaled Saline placebo

Sponsors & Collaborators

  • University of Birmingham

    collaborator OTHER

  • University of Oxford

    lead OTHER

Principal Investigators

  • Helen McShane · University of Oxford

  • Paul Moss · University of Birmingham

  • Marc Lipman · Royal Free Hostpital

  • Felicity Perrin · King's College Hospital NHS Trust

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2018-10-04
Completion
2018-10-04

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02532036 on ClinicalTrials.gov