Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy

Summary

In Parkinson's disease, Multiple Sclerosis and depressed patients treated with electroconvulsive therapy, cognitive dysfunction is prevalent. However, treatment of these dysfunctions is in its infancy.

The purpose of this study is 1) to assess the feasibility of a randomized controlled trial using an online computerized intervention for training cognitive abilities in the three patient groups and 2) to estimate the effect of the online training on objectively and subjectively measured cognitive functions.

The investigators hypothesize that patients using online cognitive training will improve more on cognitive functions, as compared to patients using an active control condition.

Conditions

• Idiopathic Parkinson's Disease
• Multiple Sclerosis
• Elderly Post Electric Convulsive Therapy

Interventions

BEHAVIORAL

Online cognitive training

The intervention is a computerized, online training programme which aims to train several cognitive abilities; especially the executive functions, attention, working memory and processing speed. The mental processes that are appealed to by the intervention are similar to processes that are trained in classic face-to-face training methods. Both the intervention protocol and the active control condition will contain several games that have the participant train cognitive functions/perform cognitive activities for 8 weeks, 3 times a week, 45-60 minutes each session.

BEHAVIORAL

Active control condition

The active control condition consists of cognitive activities that do not intend to train cognitive functions based on 'cristallized intelligence', such as trivia. Both the intervention protocol and the active control condition will contain several games that have the participant train cognitive functions/perform cognitive activities for 8 weeks, 3 times a week, 45-60 minutes each session.

Sponsors & Collaborators

• Parnassia Bavo Groep

  collaborator UNKNOWN

• GGZ inGeest

  collaborator OTHER

• Amsterdam UMC, location VUmc

  lead OTHER

Principal Investigators

• Odile A. Van den Heuvel, MD PhD · Amsterdam UMC, location VUmc

• Chris Vriend, PhD · Amsterdam UMC, location VUmc

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

30 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-03-31

Primary Completion

2017-06-30

Completion

2017-07-07

Countries

• Netherlands

Study Locations