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Effect of ACE-Inhibition on Microvascular Function in Women With Assessed Microvascular Dysfunction

NCT02525081 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 63

Last updated 2017-02-09

No results posted yet for this study

Summary

The aim of this study is to explore effects of long term treatment with ACE-inhibitor on the small vessel function assessed by coronary flow reserve (CFR) by transthoracic echocardiography and flow mediated dilation in normotensive patients with small vessel disease (CFR\<2.2) and Angina Pectoris but no obstructive coronary artery disease.

Conditions

  • Microvascular Angina

Interventions

DRUG

Ramipril (ACE-inhibitor)

up to 10 mg

DRUG

placebo

up to 10 mg

Sponsors & Collaborators

  • Bispebjerg Hospital

    lead OTHER

Principal Investigators

  • Eva Prescott, professor · Sponsor GmbH

  • Marie Michelsen, MD · Principal Investigator

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
86 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-07-31
Primary Completion
2016-07-31
Completion
2016-07-31

Countries

  • Denmark

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02525081 on ClinicalTrials.gov