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The Lung Microbiome in Sarcoidosis

NCT02520323 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 21

Last updated 2017-06-05

No results posted yet for this study

Summary

The objective of this study is to determine the presence of bacterial species, and the immunologic and molecular mechanisms of granuloma formation that might be involved in the pathogenesis of sarcoidosis. The investigators will collect peripheral blood and bronchoalveolar lavage fluid samples to isolate bacterial DNA and blood monocytes and lymphocytes. Specimens will be obtained from patients with sarcoidosis, with non-sarcoid lung disease, and healthy volunteers to directly compare the bacterial species present and the characteristics of cells thought to be involved in granuloma formation.

Conditions

  • Sarcoidosis

Interventions

OTHER

Blood draw

PROCEDURE

Bronchoscopy

BEHAVIORAL

Questionnaires

Sponsors & Collaborators

Principal Investigators

  • Eric S White, MD · University of Michigan

Eligibility

Min Age
30 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-06-30
Primary Completion
2017-06-30
Completion
2017-06-30

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02520323 on ClinicalTrials.gov