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Tumor-specific T Cells in Lung Cancer

NCT02515760 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2024-12-12

No results posted yet for this study

Summary

Non-small cell lung cancer is characterized by aggressive growth and treatment resistance. New approaches include immunotherapeutic strategies but spontaneous immune responses against tumor antigens remain unclear. The aim of this study is to characterize localization and frequencies of spontaneously induced memory T cells specific for a panel of tumor-associated antigens in peripheral blood and bone marrow of non-small cell lung cancer patients.

Conditions

Interventions

PROCEDURE

Bone marrow aspiration from the iliac crest

DEVICE

Illinois bone marrow aspiration neddle

Sponsors & Collaborators

  • German Cancer Research Center

    collaborator OTHER

  • Heidelberg University

    collaborator OTHER

  • University Hospital Heidelberg

    lead OTHER

Principal Investigators

  • Seyer Safi, MD, PhD · Division Thoracic Surgery, Technical University of Munich, Munich, Germany

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
79 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2018-06-30
Completion
2025-09-30

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02515760 on ClinicalTrials.gov