Pediatric Arm of DZL All Age Asthma Cohort

Summary

Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood. Therefore, deciphering underlying determinants for different childhood and adult asthma phenotypes is urgently needed to develop personalized treatment approaches targeting distinct underlying mechanisms. Thereby, secondary prevention early in the disease process can also be achieved. The decoding of such mechanisms and their translation to the individual patient is the aim of the Disease Area Asthma Allergy of the 'German Centre for Lung Research' (DZL).

Conditions

• Asthma
• Wheeze
• Hypersensitivity
• Endophenotype

Sponsors & Collaborators

• German Federal Ministry of Education and Research

  collaborator OTHER_GOV

• German Center for Lung Research

  collaborator OTHER

• Comprehensive Pulmonary Center Munich

  collaborator UNKNOWN

• Airway Research Center North

  collaborator UNKNOWN

• Biomedical Research in Endstage and Obstructive Lung Disease Hannover

  collaborator UNKNOWN

• Translational Lung Research Center Heidelberg

  collaborator UNKNOWN

• Universities of Giessen and Marburg Lung Center

  collaborator UNKNOWN

• LMU Klinikum

  lead OTHER

Principal Investigators

• Bianca Schaub, MD · Klinikum der Universitaet Muenchen, Comprehensive Pulmonary Center Munich

• Gesine Hansen, MD · Biomedical Research in Endstage and Obstructive Lung Disease Hannover

• Folke Brinkmann, MD · Airway Research Center North

Eligibility

Min Age

6 Months

Max Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-01-31

Primary Completion

2027-12-31

Completion

2027-12-31

Countries

• Germany

Study Locations