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Establishing of Neuronal-like Cells From Patients With Cisplatin-Induced Peripheral Neuropathy

NCT02492360 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2018-02-28

No results posted yet for this study

Summary

This study targets patients with cisplatin-induced peripheral neuropathy and will allow us to: a) study peripheral neuropathy in diverse human sensory neurons in ways that were not possible previously; b) gain insight on druggable targets to treat or prevent this devastating side effect of chemotherapy; c) provide a human cellular model that can be used for screening of drugs to determine if they are neurotoxic. The combination of patient information and in vitro measurements provides a highly relevant and clinically useful model for studies aimed to impact treatment selection for the individual cancer patient.

Conditions

  • Peripheral Nervous System Diseases
  • Testicular Neoplasms

Interventions

PROCEDURE

Blood sample collection

Six tubes of blood will be collected during one blood draw.

BEHAVIORAL

Report of peripheral neuropathy after cisplatin therapy

Twenty questions about the peripheral neuropathy the patient is currently experiencing, and twenty questions about the worst peripheral neuropathy the patient ever experienced after cisplatin treatment.

Sponsors & Collaborators

  • Costantine Albany

    lead OTHER

Principal Investigators

  • Costantine Albany, MD · Indiana University School of Medicine

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-12-31
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02492360 on ClinicalTrials.gov