MPDL3280A-treatment-IST-UMCG
NCT02478099 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 81
Last updated 2024-05-03
Summary
To be able to evaluate the investigational imaging - 89Zr-MPDL3280A-PET, 89Zr-CD8 imaging and 18F-FB-IL2-PET - as complementary tools for selection of patients to be treated with MPDL3280A, within this treatment trial the investigators will assess safety, tolerability and anti-tumor activity of MPDL3280A in cancer patients, who have undergone investigational imaging.
Conditions
- Locally Advanced or Metastatic Solid Tumors
Interventions
- DRUG
-
MPDL3280A
Anti-PD-L1 antibody
Sponsors & Collaborators
-
University Medical Center Groningen
lead OTHER
Principal Investigators
-
Elisabeth de Vries, Professor · UMCG
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-02-24
- Primary Completion
- 2023-09-19
- Completion
- 2024-07-31
Countries
- Netherlands
Study Locations
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