Trial Outcomes & Findings for A See and Treat Paradigm for Cervical Pre-cancer (NCT NCT02477124)

NCT ID: NCT02477124

Last Updated: 2023-05-18

Results Overview

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

514 participants

Primary outcome timeframe

Up to approximately 10 minutes

Results posted on

2023-05-18

Participant Flow

Cervical images obtained across 6 countries to build a database of 1000+ images to develop AI software for cervical cancer screening.

Participant milestones

Participant milestones
Measure
Transvaginal Digital Colposcope (TVCD)
Each enrolled patient will undergo the standard of care for cervical cancer screening at her institution, and then the trans-vaginal colposcope will be used to collect digital images of the cervix. transvaginal digital colposcope (TVDC): TVDC is a miniature colposcope used to obtain images of cervical tissue.
Overall Study
STARTED
514
Overall Study
COMPLETED
514
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A See and Treat Paradigm for Cervical Pre-cancer

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Transvaginal Digital Colposcope (TVCD)
n=514 Participants
Each enrolled patient will undergo the standard of care for cervical cancer screening at her institution, and then the trans-vaginal colposcope will be used to collect digital images of the cervix. transvaginal digital colposcope (TVDC): TVDC is a miniature colposcope used to obtain images of cervical tissue.
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
514 Participants
n=99 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
Sex: Female, Male
Female
514 Participants
n=99 Participants
Sex: Female, Male
Male
0 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
200 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
314 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
Race (NIH/OMB)
Asian
125 Participants
n=99 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
Race (NIH/OMB)
Black or African American
189 Participants
n=99 Participants
Race (NIH/OMB)
White
200 Participants
n=99 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Region of Enrollment
Tanzania
100 participants
n=99 Participants
Region of Enrollment
Zambia
89 participants
n=99 Participants
Region of Enrollment
Peru
200 participants
n=99 Participants
Region of Enrollment
India
125 participants
n=99 Participants

PRIMARY outcome

Timeframe: Up to approximately 10 minutes

Population: We have SOC Images from these 514 participants AND the images obtained with our research device. Therefore we have 2 photos for each step in the colposcopy procedure process

Outcome measures

Outcome measures
Measure
Transvaginal Digital Colposcope (TVCD)
n=514 Participants
Each enrolled patient will undergo the standard of care for cervical cancer screening at her institution, and then the trans-vaginal colposcope will be used to collect digital images of the cervix. transvaginal digital colposcope (TVDC): TVDC is a miniature colposcope used to obtain images of cervical tissue.
Number of Participants for Which the Standard of Care Diagnosis and the Diagnosis of the TVDC Image Agree
514 Participants

Adverse Events

Transvaginal Digital Colposcope (TVCD)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Jennifer Gallagher

Duke University

Phone: 9199701551

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place