Clinical Trial of Lurbinectedin (PM01183) in Selected Advanced Solid Tumors
NCT02454972 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 345
Last updated 2023-03-02
Summary
Multicenter, open-label, exploratory, phase II clinical trial to evaluate the efficacy and safety of PM01183 in previously treated patients with advanced solid tumors
Conditions
Interventions
- DRUG
-
lurbinectedin (PM01183)
Sponsors & Collaborators
-
PharmaMar
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-08-25
- Primary Completion
- 2020-09-18
- Completion
- 2020-09-18
Countries
- United States
- Belgium
- France
- Germany
- Italy
- Spain
- Sweden
- Switzerland
- United Kingdom
Study Locations
More Related Trials
-
Study of PM01183 in Non-Colorectal Cancer Patients as a Days 1 and 8 Intravenous Short Infusion Every 3 Weeks
NCT01405391 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors
NCT04272034 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of JNJ-70218902 in Participants With Advanced Stage Solid Tumors
NCT04397276 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluate Eribulin ORA in Subjects With Solid Tumors
NCT04013217 ·Status: TERMINATED ·Phase: PHASE1
-
Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors
NCT04336241 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Clinical Trial of PM54 in Advanced Solid Tumors Patients.
NCT05841563 ·Status: RECRUITING ·Phase: PHASE1
-
First Phase Clinical Trial of Single Agent MBF-362 in Solid Tumors
NCT05940571 ·Status: COMPLETED ·Phase: PHASE1
-
PM534 Administered Intravenously to Patients With Advanced Solid Tumors
NCT05835609 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of YL242 in Subjects With Advanced Solid Tumors
NCT07197827 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors
NCT00820560 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors
NCT03821935 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase I Study of PM02734 in Subjects With Advanced Malignant Solid Tumors
NCT00404521 ·Status: TERMINATED ·Phase: PHASE1
-
Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor
NCT05146440 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors
NCT05126433 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001)
NCT03833427 ·Status: TERMINATED ·Phase: PHASE1
-
Dose-Finding and Safety Study for Oral Single-Agent to Treat Advanced Malignancies
NCT02030067 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of AS1411 in Advanced Solid Tumours
NCT00881244 ·Status: COMPLETED ·Phase: PHASE1
-
A First-in-Human Trial of Safety and Efficacy of GEN1078 in Participants With Solid Tumors
NCT06771921 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Study of CLR457 Administered Orally in Adult Patients With Advanced Solid Malignancies
NCT02189174 ·Status: TERMINATED ·Phase: PHASE1
-
Phase 1 Study of RBN-2397, an Oral PARP7 Inhibitor, in Patients With Solid Tumors
NCT04053673 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors
NCT06873789 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Cabazitaxel vs. Vinflunine in Metastatic or Locally Advanced Transitional Cell Carcinoma of the Urothelium (TCCU)
NCT01830231 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors
NCT06859762 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Clinical Study With Investigational Compound LTT462 in Adult Patients With Specific Advanced Cancers.
NCT02711345 ·Status: TERMINATED ·Phase: PHASE1
-
Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Participants With Advanced Solid Tumors (P04722, MK-7454-004)
NCT00954512 ·Status: TERMINATED ·Phase: PHASE1/PHASE2