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TVEC and Preop Radiation for Sarcoma (4 ml Dose)

NCT02453191 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2024-06-20

Study results available
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Summary

The purpose of this research study is to determine the safety and tolerability of talimogene laherparepvec when combined with radiation therapy.

Approximately 30 people will take part in this study conducted by investigators at the University of Iowa.

Conditions

  • Soft Tissue Sarcoma

Interventions

DRUG

Talimogene Laherparepvec

Talimogene Laherparepvec

RADIATION

Radiotherapy

Concurrent Preoperative Radiation. External Beam Radiation Therapy (EBRT) will be given at the standard dose for resectable soft tissue sarcomas. according to the NCCN sarcoma guidelines.

Sponsors & Collaborators

  • Amgen

    collaborator INDUSTRY

  • University of Iowa

    lead OTHER

Principal Investigators

  • John Rieth, MD · University of Iowa

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-07-13
Primary Completion
2019-01-22
Completion
2023-03-10
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02453191 on ClinicalTrials.gov