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Continuous Venovenous Hemofiltration Versus Conventional Treatment for Acute Severe Hypernatremia

NCT02449382 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2015-07-13

No results posted yet for this study

Summary

The patients with severe hypernatremia who received conventional treatment are often undertreated. Continuous venovenous hemofiltration (CVVH) can effectively remove solute or water from circulation system. Several case reports demonstrated that CVVH could effectively decrease serum sodium concentration of the patients with severe hypernatremia. The use of CVVH for acute severe hypernatremia in critically ill patients could improve patient survival by effectively decreasing the serum sodium concentration to a normal level.

Conditions

  • Hypernatremia
  • Critically Ill

Interventions

PROCEDURE

continuous venovenous hemofiltration

If the serum sodium concentration \>150mmol/L, When filter occurred clotting, replace the filter to CVVH treatment

DRUG

Control group

If the serum sodium concentration ≤150mmol/L, When filter occurred clotting, as the end of treatment.

Sponsors & Collaborators

  • Air Force Military Medical University, China

    lead OTHER

Principal Investigators

  • Shiren Sun, M.D. · the First Affiliated Hospital of Fourth Military Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-06-30
Primary Completion
2017-06-30
Completion
2017-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02449382 on ClinicalTrials.gov