Trial Outcomes & Findings for Pilot Study for Imaging of the Esophagus Using a Tethered Capsule OCT Endomicroscopy in the Primary Care Setting (NCT NCT02445027)

NCT ID: NCT02445027

Last Updated: 2023-01-17

Results Overview

Number of Participants able to swallow the capsule successfully. An investigator will assess the quality of the recorded images and movies obtained with each exam after imaging has been completed. This is a feasibility study and was not used for any diagnosis.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

60 participants

Primary outcome timeframe

Approximate 20min visit (5min image acquisition)

Results posted on

2023-01-17

Participant Flow

A total number of 60 Participants were enrolled in the study

Participant milestones

Participant milestones
Measure
Feasibility of Tethered Capsule Endomicroscopy
Number of participants able to swallow the capsule and capture OCT images successfully in the PCP setting.
Overall Study
STARTED
60
Overall Study
COMPLETED
45
Overall Study
NOT COMPLETED
15

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Pilot Study for Imaging of the Esophagus Using a Tethered Capsule OCT Endomicroscopy in the Primary Care Setting

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Feasibility
n=60 Participants
Number of participants able to swallow the capsule and capture OCT images successfully.
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
14 Participants
n=99 Participants
Age, Categorical
>=65 years
46 Participants
n=99 Participants
Sex: Female, Male
Female
35 Participants
n=99 Participants
Sex: Female, Male
Male
25 Participants
n=99 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
Race (NIH/OMB)
Asian
3 Participants
n=99 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
Race (NIH/OMB)
Black or African American
6 Participants
n=99 Participants
Race (NIH/OMB)
White
49 Participants
n=99 Participants
Race (NIH/OMB)
More than one race
2 Participants
n=99 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Region of Enrollment
United States
60 Participants
n=99 Participants

PRIMARY outcome

Timeframe: Approximate 20min visit (5min image acquisition)

Number of Participants able to swallow the capsule successfully. An investigator will assess the quality of the recorded images and movies obtained with each exam after imaging has been completed. This is a feasibility study and was not used for any diagnosis.

Outcome measures

Outcome measures
Measure
Feasibility
n=60 Participants
Feasibility is measured by the total number of Participants able to swallow the capsule successfully.
Feasibility of Esophageal Imaging in Subjects Who Successfully Swallow the OCT Capsule in the Primary Care Setting.
45 Participants

Adverse Events

MGH OCT Imaging Capsule

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Anna Gao RN.

Massachusetts General Hospital

Phone: 617-643-6092

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place