Comparative Autoantibody and Immunologic Cell Marker Study
NCT02422875 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 2500
Last updated 2025-09-30
Summary
The purpose of this study is to compare immune phenotype, function, and specificity of B lymphocytes from different developmental stages in autoimmune patients to B cells from infectious disease patients and healthy controls.
Conditions
- Autoimmune Diseases
- Lupus Erythematosus, Systemic
- Communicable Diseases
Sponsors & Collaborators
-
National Institute of Allergy and Infectious Diseases (NIAID)
collaborator NIH -
Emory University
lead OTHER
Principal Investigators
-
Ignatio Sanz, MD · Emory University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-08-31
- Primary Completion
- 2028-05-31
- Completion
- 2028-05-31
Countries
- United States
Study Locations
More Related Trials
-
Phase 1 Study of Belimumab in Subjects With Systemic Lupus Erythematosus (SLE)
NCT00657007 ·Status: COMPLETED ·Phase: PHASE1
-
Autoimmunity in Sisters of Lupus Patients
NCT01076101 ·Status: COMPLETED
-
C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease
NCT06935474 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Disease Progression and Activity in Patients With Systemic Lupus Erythematosus
NCT00339261 ·Status: COMPLETED
-
Role of Antibodies in Cognitive Dysfunction in Patients With Systemic Lupus Erythematosus
NCT00042523 ·Status: COMPLETED
-
BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus
NCT06340750 ·Status: RECRUITING ·Phase: PHASE1
-
Determining the Responses and Impact of Rituximab-instigated Cell Depletion on T Cells in People With SLE
NCT01702038 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of Rontalizumab in Patients With Moderately to Severely Active Systemic Lupus Erythematosus
NCT00962832 ·Status: COMPLETED ·Phase: PHASE2
-
A Continuation Trial for Subjects With Lupus Who Completed Protocol HGS1006-C1056 in the United States
NCT00724867 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical and Diagnostic Value of Ribosomal p2 Autoantibodies in Systemic Lupus Erythematosus
NCT05179018 ·Status: UNKNOWN
-
Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE
NCT04726553 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Utilizing Qualitative and Quantitative Methods to Understand a New Model of Type 1 and 2 Systemic Lupus Erythematosus (SLE)
NCT05426902 ·Status: COMPLETED ·Phase: NA
-
A Study of RD06-04 in Patients With Active Autoimmune Diseases
NCT06548620 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Phase II Pilot Study of Cytarabine for Refractory Systemic Lupus Erythematosus
NCT00004643 ·Status: COMPLETED ·Phase: PHASE2
-
Prediction of Outcome of Lupus Nephritis
NCT02403115 ·Status: UNKNOWN
-
Comparison of Clinical and Serological Differences Among Juvenile, Adult, and Late-onset Systemic Lupus Erythematosus
NCT05724940 ·Status: UNKNOWN
-
INFLAMmatory BiomarkErs in COVID-19 Participants and Severity of Disease
NCT05175846 ·Status: UNKNOWN
-
A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus
NCT02725515 ·Status: COMPLETED ·Phase: PHASE2
-
PRediction Of Flares In Lupus With autoantibodiEs and Chemokines
NCT04951427 ·Status: UNKNOWN
-
Universal Anti-CD70 CAR-T (CHT101) Cell Therapy for Relapsed Refractory Systemic Lupus Erythematosus
NCT06946485 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
NCT05866861 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Evaluating the Immune Response to COVID19 Vaccination in Immunodeficient Patients
NCT05286242 ·Status: ACTIVE_NOT_RECRUITING
-
Anti-ficolin-2 Autoantibodies in Lupus Nephritis
NCT03063281 ·Status: COMPLETED
-
Safety and Efficacy of PRG-2311 for Refractory Lupus Nephritis and IgG4-Related Disease
NCT06497361 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
NCT07175285 ·Status: RECRUITING