Furosemide Stress Test as a Predictor of Tubular Function in Chronic Kidney Disease
NCT02417883 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2015-04-16
Summary
In kidney diseases, tubule-interstitium has become much more relevant, as formerly only the glomerulus was considered to have the main importance. Kidney's tubular atrophy and interstitital fibrosis is now recognized as long term prognostic value. We aim to evaluate the function of the kidney's tubule-interstitium through furosemide excretion after intravenous administration of this drug, and correlate the rate of excretion of furosemide with interstitial fibrosis findings in scheduled kidney biopsy for patients with chronic kidney disease.
Conditions
Interventions
- DRUG
-
Furosemide
Evaluate urinary excretion rate fo furosemide
Sponsors & Collaborators
-
Instituto Nacional de Cardiologia Ignacio Chavez
lead OTHER
Principal Investigators
-
Magdalena Madero, MD · Chief of the Nephrology Department
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-04-30
- Primary Completion
- 2016-04-30
- Completion
- 2017-04-30
Countries
- Mexico
Study Locations
More Related Trials
-
A Study Of Mircera In Patients With Kidney Disease Who Are Not On Dialysis
NCT02490514 ·Status: COMPLETED
-
Utility of Prolonged-release Pirfenidone in the Progression of Chronic Kidney Disease
NCT02408744 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Hemoglobin Maintenance in Pediatric ESRD (End-stage Renal Disease) Patients by Ferric Pyrophosphate Citrate (FPC)
NCT04239391 ·Status: UNKNOWN ·Phase: PHASE3
-
Once-A-Month Steroid Treatment for Patients With Focal Segmental Glomerulosclerosis
NCT00004990 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Pharmacology Study of TS-143 in Nondialysis and Hemodialysis Patients with Chronic Kidney Disease
NCT03581071 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Profile and Pharmacodynamic Characteristics of a Furosemide High Dosage Formulation in Patients With Chronic Renal Failure Undergoing Peritoneal Dialysis
NCT01724788 ·Status: COMPLETED ·Phase: PHASE1
-
Fu-zheng-qu-zhuo Oral Liquid Improves Renal Function in Patients of CKD Stage 3 and 4
NCT02275468 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Suramin in Subjects With Furosemide-Resistant AKI
NCT04496596 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparative Evaluation of Pharmacokinetics After CKD-501 Between Renal Impaired and Normal Renal Function Subjects
NCT02007941 ·Status: COMPLETED ·Phase: PHASE1
-
Mass Balance Study of JTZ-951 in Subjects With End-stage Renal Disease on Hemodialysis
NCT02805244 ·Status: COMPLETED ·Phase: PHASE1
-
Trial to Assess the Efficacy and Safety of Nafamostat Mesilate During Continuous Renal Replacement Therapy
NCT02478242 ·Status: COMPLETED ·Phase: PHASE4
-
A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.
NCT05524051 ·Status: TERMINATED ·Phase: PHASE2
-
Fruquintinib Renal Impairment Study
NCT05216354 ·Status: COMPLETED ·Phase: PHASE1
-
Renal Impairment Study of PF-06700841
NCT04260464 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 2, Multi-center, Open-label, Dose-finding Trial to Investigate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of OPC-41061 in Patients With Chronic Renal Failure Undergoing Hemodialysis or Hemodiafiltration
NCT01876381 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Pharmacokinetics of FG-3019 in Adolescents and Adults With Focal Segmental Glomerulosclerosis (FSGS)
NCT00782561 ·Status: TERMINATED ·Phase: PHASE1
-
Transcriptome Analysis in Idiopathic Nephrotic Syndrome: Steroid Responsiveness
NCT06325137 ·Status: RECRUITING
-
Prospective Study Evaluating the Effect of Repository Corticotropin in the Treatment of Various Nephrotic Syndromes
NCT01021540 ·Status: COMPLETED ·Phase: PHASE4
-
Phase I Study of Alpha-Melanocyte Stimulating Hormone in Patients With Acute Renal Failure
NCT00004496 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Study of Calderasib (MK-1084) in Participants With Renal Impairment (MK-1084-010)
NCT06814119 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis
NCT05624723 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Study to Compare the Pharmacokinetics and Safety of D113 With CKD-349 in Healthy Volunteers
NCT04952506 ·Status: COMPLETED ·Phase: PHASE1
-
A Renal Impairment Study for PF-04965842
NCT03660241 ·Status: COMPLETED ·Phase: PHASE1
-
Antiproteinuric Agents and Fabry Disease
NCT00343577 ·Status: COMPLETED
-
Pharmacokinetics of Single-Dose Oral Ranolazine in Hemodialysis Patients
NCT01435174 ·Status: COMPLETED ·Phase: PHASE4