A Controlled Study of the Aqueous Humor Dynamics of AR-13324 Ophthalmic Solution in Healthy Adult Volunteers
NCT02406287 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2016-09-13
Summary
To evaluate the effect of netarsudil (AR-13324) ophthalmic solution on aqueous humor dynamics relative to its placebo.
Conditions
- Healthy Subjects
Interventions
- DRUG
-
Netarsudil (AR-13324) Ophthalmic Solution
Topical ophthalmic solution
- DRUG
-
Netarsudil (AR-13324) Ophthalmic Solution Placebo
Ophthalmic solution once a day
Sponsors & Collaborators
-
Aerie Pharmaceuticals
lead INDUSTRY
Principal Investigators
-
Nancy Ramirez · Aerie Pharmaceuticals
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-04-30
- Primary Completion
- 2016-04-30
- Completion
- 2016-04-30
Countries
- United States
Study Locations
More Related Trials
-
Efficacy Study of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery
NCT00853970 ·Status: COMPLETED ·Phase: PHASE3
-
Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients
NCT00352807 ·Status: COMPLETED ·Phase: NA
-
Pain Reduction With Topical Bromfenac Versus Artificial Tear After Intravitreal Injection.
NCT06130384 ·Status: COMPLETED ·Phase: PHASE4
-
Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty
NCT04057053 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis
NCT04222712 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% 2 Times Daily (BID) and Bromfenac 0.09% 2 Times Daily (BID)
NCT01023724 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery
NCT02329743 ·Status: COMPLETED ·Phase: PHASE2
-
Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients: Trough Drug Effects
NCT00469690 ·Status: COMPLETED ·Phase: PHASE4
-
Aqueous Humor Concentration of InSite Vision (ISV) 303 (Bromfenac in DuraSite) to Bromday Once Daily (QD) Prior to Cataract Surgery
NCT01387464 ·Status: COMPLETED ·Phase: PHASE2
-
Study to See How Well an Eye Drop, SURF-201, Works and What Side Effects There Are in Cataract Surgery Subjects
NCT04324359 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery
NCT01367249 ·Status: COMPLETED ·Phase: PHASE3
-
Comparing Post-intravitreal Injection Pain Scores Using Loteprednol, Bromfenac Sodium, and Artificial Tears Over a 24-hour Period
NCT07090044 ·Status: COMPLETED ·Phase: PHASE4
-
Prednisolone Acetate Eye Drops for Pain Intervention in Second Eye Cataract Surgery
NCT06614348 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery
NCT05528172 ·Status: COMPLETED ·Phase: PHASE3
-
An Observational, Qualitative Study Assessing Eye Drop Administration
NCT05307081 ·Status: UNKNOWN
-
Acular LS vs. Nevanac in Post op Inflammation Following Cataract Surgery
NCT00348582 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Pain Sensation During Single Use of Two Topical Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
NCT00869219 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study to Compare Ocular Safety and Tolerability of Eye Drops Containing Prednisolone Acetate in Patients With Intraocular Inflammation After Cataract Surgery
NCT00170729 ·Status: COMPLETED ·Phase: PHASE4
-
Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients
NCT00347503 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Ketorolac for the Treatment of Inflammation and Pain Associated With Cataract Surgery
NCT00524264 ·Status: COMPLETED ·Phase: PHASE3
-
Bromfenac 0.09% vs Ketorolac 0.4% for Cyclosporine Induction Phase
NCT00520260 ·Status: COMPLETED ·Phase: PHASE4
-
Cross-Over Evaluation of Two Lubricating Eye Drops
NCT00493662 ·Status: COMPLETED ·Phase: PHASE4
-
Safety/Efficacy of Bromfenac Ophthalmic Solution for Ocular Inflammation and Pain Associated With Cataract Surgery
NCT00333918 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy Study of rEV131 in the Treatment of Ocular Inflammation After Cataract Surgery
NCT00353964 ·Status: UNKNOWN ·Phase: PHASE2
-
Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections
NCT03079713 ·Status: COMPLETED ·Phase: NA