MedTrace Logo

Elucidating the Influence of Lactulose Intake on the Gut Microbiota Composition

NCT02397512 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2017-07-11

No results posted yet for this study

Summary

This study will test the influence of lactulose of the human gut microbiota. Healthy volunteers will ingest 50g of lactulose and donate stool samples 1 day before as well as 1-2 days and 14 days after the test. Using sequencing and metabolomics techniques the investigators will identify changes in microbiota composition upon lactulose exposure.

Conditions

  • Changes in Gut Microbiota Composition After Lactulose Exposure

Interventions

DRUG

application of lactulose

Subjects will ingest 50g of lactulose once

OTHER

application of sucrose

Subjects will ingest 50g of sucrose once

Sponsors & Collaborators

  • Swiss Federal Institute of Technology in Zurich (ETHZ)

    collaborator UNKNOWN

  • University of Zurich

    lead OTHER

Principal Investigators

  • Benjamin Misselwitz, MD · University of Zurich

  • Gerhard Rogler, MD PhD · University of Zurich

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-02-28
Primary Completion
2015-10-01
Completion
2015-10-01

Countries

  • Switzerland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02397512 on ClinicalTrials.gov