Stereotactic Prostate Adaptive Radiotherapy Utilising Kilovoltage Intrafraction Monitoring
NCT02397317 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 49
Last updated 2026-05-19
Summary
The SPARK trial is testing the use of Kilovoltage Intrafraction Monitoring in prostate cancer patients being treated with Stereotactic Prostate Adaptive Radiotherapy. The researchers expect this trial to result in better targeted prostate cancer patient outcomes with lower toxicity. The potential application of Kilovoltage Intrafraction Monitoring to other tumour sites will pave the way for additional trials with Australasian radiation oncology leading the world.
Conditions
Interventions
- RADIATION
-
Multi-fraction SABR
All participants will receive Multi-Fraction SABR; 36.25 Gy (PTV D95) in 5 Fractions within 2-5 weeks
Sponsors & Collaborators
-
Trans Tasman Radiation Oncology Group
collaborator OTHER -
University of Sydney
lead OTHER
Principal Investigators
-
Paul Keall · University of Sydney
-
Jarad Martin · Calvary Mater Newcastle
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-02-29
- Primary Completion
- 2020-03-30
- Completion
- 2020-06-19
Countries
- Australia
Study Locations
More Related Trials
-
Stereotactic Body Radiation Therapy in Treating Patients With Localized Prostate Cancer That Have Undergone Surgery
NCT03541850 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Stereotactic Body Radiotherapy for Stage I-III Prostate Cancer
NCT02334579 ·Status: UNKNOWN ·Phase: NA
-
Stereotactic Ablative Radiotherapy (SABR) of Pelvis and Prostate Targets For High Risk Prostate Cancer
NCT02353819 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
MRI-guided Ultrahypofractionated SBRT Prostate Program
NCT07132658 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Single Fraction HDR Brachytherapy Plus Hypofractionated EBRT for Low-risk Prostate Cancer: Phase II Trial
NCT02283346 ·Status: UNKNOWN ·Phase: PHASE2
-
SPORT High-Risk Trial Evaluating SABR in Prostate Cancer
NCT03253978 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Dose Escalation For INtraprostatic LEsions
NCT05851547 ·Status: RECRUITING ·Phase: PHASE2
-
SRT in Combination With Pembrolizumab in Patients With Recurrent Prostate Cancer After Radical Prostatectomy
NCT04931979 ·Status: RECRUITING ·Phase: PHASE2
-
Fairly Brief Androgen Suppression and Stereotactic Radiotherapy for High Risk Prostate Cancer - Protocol 2
NCT02229734 ·Status: COMPLETED ·Phase: PHASE2
-
Two-fraction Proton Therapy With MRI Guidance for Prostate Cancer: A Phase II Trial
NCT07130682 ·Status: RECRUITING ·Phase: NA
-
Adaptive MR-guided SBRT for Localized Prostate Cancer
NCT04571762 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Early Magnetic Resonance Imaging Response of the Dominant Intraprostatic Lesion After Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer and Correlation With Prostate Specific Antigen Response
NCT06822491 ·Status: ACTIVE_NOT_RECRUITING
-
High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer
NCT05754580 ·Status: RECRUITING ·Phase: NA
-
Single Arm Trial of Preoperative Stereotactic Body Radiation Therapy (SBRT) for T3a or Gleason Grade Group 4 Prostate Cancer
NCT03748719 ·Status: WITHDRAWN ·Phase: NA
-
Comparing Hypofractionated Radiotherapy Boost to Conventionally Fractionated
NCT02300389 ·Status: COMPLETED ·Phase: NA
-
Magnetic Resonance Guided Focal Stereotactic Body Radiation Therapy for Localized Prostate Cancer
NCT02163317 ·Status: COMPLETED ·Phase: NA
-
Darolutamide + Consolidation Radiotherapy in Advanced Prostate Cancer Detected by PSMA
NCT04319783 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Stereotactic Body Radiation Therapy With Boost Using Urethral-Sparing Intensity-Modulated Radiation Therapy Planning in Treating Patients With Prostate Cancer
NCT02470897 ·Status: COMPLETED ·Phase: NA
-
Two-Fraction Ultrahypofractionated Radiotherapy With Focal Boost for Intermediate Risk, Localized Prostate Cancer
NCT06518226 ·Status: RECRUITING ·Phase: NA
-
Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer
NCT06990542 ·Status: RECRUITING ·Phase: PHASE2
-
Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])
NCT05038332 ·Status: RECRUITING ·Phase: PHASE2
-
Prostate Boost Irradiation With Stereotactic Body RT (SBRT)
NCT03380806 ·Status: UNKNOWN ·Phase: PHASE2
-
Improving Sexual Quality of Life - Randomized Trial of Two vs Five MRI Guided SABR Treatments for Prostate Cancer
NCT05600400 ·Status: RECRUITING ·Phase: NA
-
Stereotactic Focal Radiotherapy as an Alternative Treatment to Active Surveillance for Low and Intermediate Risk Prostate Cancer
NCT07152067 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Stereotactic Ablative Radiation Therapy for Prostate Cancer
NCT05668351 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA