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IM Olanzapine Versus Haloperidol or Midazolam

NCT02380118 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 167

Last updated 2022-11-04

No results posted yet for this study

Summary

The purpose of this study is to determine whether intramuscular olanzapine is safer (fewer adverse events) and more effective (shorter time to sedation) than conventional haloperidol or midazolam when used in the management of acute agitation in the emergency department.

Conditions

  • Acute Agitation, Behavioural Emergency

Interventions

DRUG

Olanzapine

Intramuscular injection

DRUG

Haloperidol

Intramuscular injection

DRUG

Midazolam

Intramuscular injection

Sponsors & Collaborators

  • Queen Mary Hospital, Hong Kong

    collaborator OTHER

  • Tuen Mun Hospital

    collaborator OTHER_GOV

  • Pamela Youde Nethersole Eastern Hospital

    collaborator OTHER

  • Ruttonjee Hospital

    collaborator OTHER

  • Prince of Wales Hospital, Shatin, Hong Kong

    collaborator OTHER

  • United Christian Hospital

    collaborator OTHER

  • The University of Hong Kong

    lead OTHER

Principal Investigators

  • Esther WY Chan, PhD · The University of Hong Kong

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-12-31
Primary Completion
2019-09-30
Completion
2019-09-30

Countries

  • Hong Kong

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02380118 on ClinicalTrials.gov