Molecular Characterization of CTCs and ctDNA in Blood and Plasma Samples From Patients With Metastatic and/or Hormone-Resistant Prostate Cancer
NCT02370355 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 24
Last updated 2017-04-17
Summary
This research trial studies molecular characterization of circulating tumor cells (CTCs) and circulating tumor (ct) deoxyribonucleic acid (DNA) in blood and plasma samples from patients with prostate cancer that has spread to other places in the body and/or has not responded to previous treatment with hormones. Studying samples of blood and plasma collected from patients with prostate cancer before, during, and/or after treatment in the laboratory may help doctors learn more about changes that occur in DNA and identify the development of drug resistance.
Conditions
- Hormone-Resistant Prostate Cancer
- Metastatic Prostate Carcinoma
Interventions
- OTHER
-
Cytology Specimen Collection Procedure
Undergo collection of blood samples
- OTHER
-
Laboratory Biomarker Analysis
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Southern California
lead OTHER
Principal Investigators
-
Mitchell Gross · University of Southern California
Eligibility
- Min Age
- 19 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-12-23
- Primary Completion
- 2016-06-08
- Completion
- 2016-06-08
Countries
- United States
Study Locations
More Related Trials
-
Prospective CiRculating prOstate Cancer Predictors in HighEr Risk mCRPC studY
NCT02269982 ·Status: COMPLETED
-
Study of Blood and Urine Samples in Patients With Newly Diagnosed Localized Prostate Cancer Treated With Hormone Therapy and Radiation Therapy. ICORG 06-15
NCT00955435 ·Status: UNKNOWN
-
Testosterone in Castration-Resistant Prostate Cancer
NCT00577980 ·Status: WITHDRAWN ·Phase: PHASE2
-
Gene Mutations in Patients With Advanced Prostate Cancer That Is Not Responsive to Hormone Therapy
NCT00002924 ·Status: COMPLETED
-
Prostate Cryoablation Combined With Metronomic Cyclophosphamide for Metastatic Prostate Cancer
NCT06854250 ·Status: RECRUITING ·Phase: PHASE2
-
Biomarkers of Bone Resorption in Metastatic Prostate Cancer
NCT01233557 ·Status: COMPLETED
-
CT-2584 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Previous Therapy
NCT00004026 ·Status: TERMINATED ·Phase: PHASE2
-
Observational Longitudinal Study of Pain in Men With Metastatic Castrate-Resistant Prostate Cancer
NCT02008058 ·Status: COMPLETED
-
Expression of Molecular Markers in Circulating Tumor Cells of Metastatic Castration-Resistant Prostate Cancer
NCT03089099 ·Status: UNKNOWN
-
Biomarker-driven Intermittent Docetaxel in Metastatic Castration-resistant Prostate Cancer
NCT04918810 ·Status: TERMINATED ·Phase: PHASE2
-
Surgery in Treating Patients With Prostate Cancer
NCT00002938 ·Status: COMPLETED ·Phase: PHASE2
-
Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer
NCT03327662 ·Status: TERMINATED ·Phase: PHASE3
-
Evaluation of a Blood Biomarker to Try and Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
NCT03256630 ·Status: TERMINATED
-
Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer
NCT06326216 ·Status: ACTIVE_NOT_RECRUITING
-
Cultured Circulating Tumor Cells in Prostate and Other Cancers
NCT02123862 ·Status: UNKNOWN
-
Measurement of Circulating Tumor Cells in Prostate Cancer
NCT04101305 ·Status: UNKNOWN
-
Collection of Blood in Studying Metabolites in Patients With Prostate Cancer
NCT03485794 ·Status: TERMINATED
-
Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer
NCT02995330 ·Status: TERMINATED ·Phase: PHASE1
-
Biomarker 11-dh-TXB2 in Blood and Urine Samples From Patients With Prostate Cancer and Healthy Volunteers
NCT00984919 ·Status: COMPLETED
-
Study of TAS3681 in Metastatic Castration Resistant Prostate Cancer
NCT02566772 ·Status: COMPLETED ·Phase: PHASE1
-
Allogeneic Human Bone Marrow Derived Mesenchymal Stem Cells in Localized Prostate Cancer
NCT01983709 ·Status: TERMINATED ·Phase: PHASE1
-
Evaluation of Molecular Forms of PSA and Human Kallikrein 2 in a Cohort of Patients With Locally Resected Prostate Cancer But Biochemical Recurrence
NCT02070575 ·Status: COMPLETED
-
Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer
NCT02458716 ·Status: COMPLETED ·Phase: PHASE1
-
An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma
NCT00544440 ·Status: COMPLETED ·Phase: PHASE2
-
Nutrition and Prostate Cancer
NCT03532308 ·Status: TERMINATED ·Phase: PHASE3