Buparlisib in Patients With Relapsed and Refractory Chronic Lymphocytic Leukemia
NCT02340780 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2023-08-22
Summary
The purpose of this study is to find out what effects a new drug, buparlisib, has on chronic lymphocytic leukemia.
Conditions
Interventions
- DRUG
-
Buparlisib
Sponsors & Collaborators
- collaborator INDUSTRY
-
Canadian Cancer Trials Group
lead NETWORK
Principal Investigators
-
Sarit Assouline · McGill University - Dept. Oncology, Jewish General Hospital Site, Montreal QC Canada
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-04-27
- Primary Completion
- 2018-11-21
- Completion
- 2020-04-28
Countries
- Canada
Study Locations
More Related Trials
-
A Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
NCT01578707 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Zanubrutinib (BGB-3111) Versus Ibrutinib in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia
NCT03734016 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety and Tolerability of BMS-986403 in Participants With Relapsed and/or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT05244070 ·Status: TERMINATED ·Phase: PHASE1
-
Ibrutinib in Treating Patients With Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia
NCT02129062 ·Status: TERMINATED ·Phase: PHASE2
-
Bortezomib-based Regimen for Refractory or Relapsed Acute Lymphoblastic Leukemia
NCT06034561 ·Status: RECRUITING ·Phase: PHASE2
-
Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients
NCT04008706 ·Status: COMPLETED ·Phase: PHASE3
-
Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
NCT03331198 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Ruxolitinib Combined With Ibrutinib in Chronic Lymphocytic Leukemia Patients
NCT02912754 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Daratumumab and Ibrutinib for the Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia, DIRECT Study
NCT04230304 ·Status: TERMINATED ·Phase: PHASE2
-
Tipifarnib and Bortezomib in Treating Patients With Acute Leukemia or Chronic Myelogenous Leukemia in Blast Phase
NCT00383474 ·Status: COMPLETED ·Phase: PHASE1
-
Ibrutinib Plus Venetoclax in Subjects With Treatment-naive Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma (CLL/SLL)
NCT02910583 ·Status: COMPLETED ·Phase: PHASE2
-
Daratumumab and Ibrutinib in Treating Patients With Symptomatic Chronic Lymphocytic Leukemia
NCT03447808 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Phase II Nilotinib With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML)
NCT00129740 ·Status: COMPLETED ·Phase: PHASE2
-
Fludarabine in Treating Patients With Chronic Lymphocytic Leukemia
NCT00049075 ·Status: COMPLETED ·Phase: PHASE2
-
A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors
NCT02403271 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase II Study of Ibrutinib Plus FCR in Previously Untreated, Younger Patients With Chronic Lymphocytic Leukemia
NCT02251548 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of BNC105P Combined With Ibrutinib
NCT03454165 ·Status: COMPLETED ·Phase: PHASE1
-
Alemtuzumab/Fludarabine for Relapsed/Refractory B-cell Chronic Lymphocytic Leukemia (B-CLL)
NCT00206726 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia
NCT07061951 ·Status: RECRUITING ·Phase: PHASE2
-
506U78 in Treating Patients With Chronic Lymphocytic Leukemia That Has Not Responded to Fludarabine or Alkylating Agents
NCT00003635 ·Status: COMPLETED ·Phase: PHASE2
-
Ibrutinib in Previously Untreated Binet Stage a Chronic Lymphocytic Leukemia with Risk of Disease Progression
NCT02863718 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax
NCT04016805 ·Status: TERMINATED ·Phase: PHASE2
-
Nemtabrutinib and Lisocabtagene Maraleucel for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
NCT07194980 ·Status: RECRUITING ·Phase: PHASE2
-
Dasatinib in Relapsed Chronic Lymphocytic Leukemia
NCT00438854 ·Status: COMPLETED ·Phase: PHASE2
-
A Time-Limited Approach to Treatment With Ibrutinib for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
NCT04694560 ·Status: WITHDRAWN