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The Effects of Dexamethasone on Low Dose Interscalene Brachial Plexus Block

NCT02322242 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 182

Last updated 2020-07-15

Study results available
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Summary

A standard interscalene nerve block is performed with long acting local anesthetic (bupivacaine or ropivacaine in concentrations varying from 0.25% to 0.75%). The purpose of this study is to investigate the effect of the addition of perineural dexamethasone (4mg) to a standard ropivacaine solution (0.5%) on analgesic duration of low dose interscalene block compared to ropivacaine alone for interscalene block with systemic dexamethasone.

Ropivacaine is not an intervention as a local anesthetic is pre-requisite to performing a nerve block.

Conditions

  • Shoulder Surgery
  • Nerve Block

Interventions

DRUG

Systemic Dexamethasone

Intravenous infusion of dexamethasone (4mg)

DRUG

Perineural dexamethasone

Perinerual administration of dexamethasone (4mg)

Sponsors & Collaborators

  • The Physicians' Services Incorporated Foundation

    collaborator OTHER

  • Dr. Stephen Choi

    lead OTHER

Principal Investigators

  • Stephen Choi, MD,FRCPC,MSc · SunnybrookHealth Sciences Centre

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2019-01-31
Completion
2019-05-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02322242 on ClinicalTrials.gov